SynthesisJournal of opioid management
State-level and system-level opioid prescribing policies: The impact on provider practices and overdose deaths, a systematic review.
Synthesis in Journal of opioid management. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Regulatory Policies for Alcohol, other Psychoactive Substances and Addictive Behaviours: The Role of Level of Use and Potency. A Systematic Review.International journal of environmental research and public health · 2019Pooled it
- A Rapid Review of the Impact of Systems-Level Policies and Interventions on Population-Level Outcomes Related to the Opioid Epidemic, United States and Canada, 2014-2018.Public health reports (Washington, D.C. : 1974)Pooled it
- Multicomponent behavioral intervention to reduce exposure to anticholinergics in primary care older adults.Journal of the American Geriatrics Society · 2021Trial
- Opioid dose, duration, and risk of use disorder in Medicaid patients with musculoskeletal pain.Pain medicine (Malden, Mass.) · 2026Article
- Suicide Deaths in People With Bipolar Disorder: Characteristics and Treatments at Time of Death.Bipolar disorders · 2025Article
- Opioid prescribing trends and pain scores among adult patients with cancer in a large health system.Cancer · 2025Article
- Opioid prescription rates associated with surgery among adolescents in the United States from 2015 to 2020.Paediatric anaesthesia · 2023Article
- Adult Medical Cannabinoid Use and Changes in Prescription Controlled Substance Use.Cannabis and cannabinoid research · 2023Article
- Association Between Statewide Opioid Prescribing Interventions and Opioid Prescribing Patterns in North Carolina, 2006-2018.Pain medicine (Malden, Mass.) · 2021Article
- Changes in early high-risk opioid prescribing practices after policy interventions in Washington State.Health services research · 2021Article
- Commercial and public payer opioid analgesic prescribing policies: a case study.Substance abuse treatment, prevention, and policy · 2021Article
- Association of State-Level Opioid-Reduction Policies With Pediatric Opioid Poisoning.JAMA pediatrics · 2020Article
- Quality improvement initiative for pain management practices in primary care.Proceedings (Baylor University. Medical Center) · 2020Article
- The state of the science in opioid policy research.Drug and alcohol dependence · 2020Review
- Responsible Prescribing of Opioids for Chronic Non-Cancer Pain: A Scoping Review.Pharmacy (Basel, Switzerland) · 2020Article
- The Association of State Opioid Misuse Prevention Policies With Patient- and Provider-Related Outcomes: A Scoping Review.The Milbank quarterly · 2020Article
- Communication between pharmacists and primary care physicians in the midst of a U.S. opioid crisis.Research in social & administrative pharmacy : RSAP · 2019Article
- Association of the Use of a Mandatory Prescription Drug Monitoring Program With Prescribing Practices for Patients Undergoing Elective Surgery.JAMA surgery · 2018Observational
- The Evolving Landscape of Acute Pain Management in the Era of the Opioid Crisis.Current pain and headache reports · 2018Review
- A systematic review of strategies to improve appropriate use of opioids and to reduce opioid use disorder and deaths from prescription opioids.Canadian journal of pain = Revue canadienne de la douleur · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
objectiveIn response to persistent public health concerns regarding prescription opioids, many states and healthcare systems have implemented legislation and policies intended to regulate or guide opioid prescribing. The overall impact of these policies is still uncertain. The aim of this systematic review was to examine the existing evidence of provider-level and patient-level outcomes preimplementation and postimplementation of policies and legislation constructed to impact provider prescribing practices around opioid analgesics.
designA systematic search of MEDLINE, EMBASE, the Web of Science, and the Cochrane Database of Systematic Reviews was conducted to identify studies evaluating the impact of opioid prescribing policies on provider-level and patient-level outcomes. The systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
resultsEleven studies were included in the review. A meta-analysis was not possible due to between-study heterogeneity. Six of the studies assessed state-level policies, and five were at the level of the healthcare system or hospital. Studies showed temporal associations between policy implementation and reductions in opioid prescribing, as well as opioid-related overdoses. Results were mixed regarding the impact of policies on misuse. The majority of the studies were judged to be of low quality based on the GRADE criteria.
conclusionsThere is low to moderate quality evidence suggesting that the presence of opioid prescribing policy will reduce the amount and strength of opioid prescribed. The presence of these policies may impact the number of overdoses, but there is no clear evidence to suggest that it reduces opioid misuse.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.