Evidence map›Paper›PMID 27194170›Full record

ArticleNeuroradiology2016

Cervical spinal canal narrowing in idiopathic syringomyelia.

Aaron F Struck, Carrie M Carr, Vinil Shah, John R Hesselink, Victor M Haughton

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Clinical manifestations and radiological characteristics in patients with idiopathic syringomyelia and scoliosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Aaron F StruckDepartment of Neurology, Massachusetts General Hospital, 55 Fruit Street Wang 735, Boston, MA, 02114, USA. astruck@mgh.harvard.edu.
Carrie M CarrDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Vinil ShahDepartment of Radiology, University of California San Francisco, San Francisco, CA, USA.
John R HesselinkDepartment of Radiology, University of California San Diego, San Diego, CA, USA.
Victor M HaughtonDepartment of Radiology, University of Wisconsin, Madison, WI, USA.
Massachusetts General Hospital · USMayo Clinic in Arizona · USUniversity of California, San Diego · USUniversity of California, San Francisco · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe cervical spine in Chiari I patient with syringomyelia has significantly different anteroposterior diameters than it does in Chiari I patients without syringomyelia. We tested the hypothesis that patients with idiopathic syringomyelia (IS) also have abnormal cervical spinal canal diameters. The finding in both groups may relate to the pathogenesis of syringomyelia.

methodsLocal institutional review boards approved this retrospective study. Patients with IS were compared to age-matched controls with normal sagittal spine MR. All subjects had T1-weighted spin-echo (500/20) and T2-weighted fast spin-echo (2000/90) sagittal cervical spine images at 1.5 T. Readers blinded to demographic data and study hypothesis measured anteroposterior diameters at each cervical level. The spinal canal diameters were compared with a Mann-Whitney U test. The overall difference was assessed with a Friedman test. Seventeen subjects were read by two reviewers to assess inter-rater reliability.

resultsFifty IS patients with 50 age-matched controls were studied. IS subjects had one or more syrinxes varying from 1 to 19 spinal segments. Spinal canal diameters narrowed from C1 to C3 and then enlarged from C5 to C7 in both groups. Diameters from C2 to C4 were narrower in the IS group (p < 0.005) than in controls. The ratio of the C3 to the C7 diameters was also smaller (p = 0.004) in IS than controls. Collectively, the spinal canal diameters in the IS were significantly different from controls (Friedman test p < 0.0001).

conclusionPatients with IS have abnormally narrow upper and mid cervical spinal canal diameters and greater positive tapering between C3 and C7.

Indexed as

AdolescentAdultAgedCervical VertebraeChildChild, PreschoolDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedInfantMaleMiddle AgedReproducibility of ResultsCerebrospinal fluidCervical spinal canalCSF flow dynamicsIdiopathic syringomyelia

Identifiers

PMID27194170
OpenAlexW2402478313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.