Evidence map›Paper›PMID 27194154›Full record

ReviewMagma (New York, N.Y.)2016

Toward 20 T magnetic resonance for human brain studies: opportunities for discovery and neuroscience rationale.

Thomas F Budinger, Mark D Bird, Lucio Frydman, Joanna R Long, Thomas H Mareci, William D Rooney, Bruce Rosen, John F Schenck, Victor D Schepkin, A Dean Sherry and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Magma (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. First implementation of dynamic oxygen-17 (Magma (New York, N.Y.) · 2024
    Article
  5. Micron-resolution Imaging of Cortical Bone under 14 T Ultrahigh Magnetic Field.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Nonparametric 5D D-RJournal of magnetic resonance (San Diego, Calif. : 1997) · 2022
    Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Frontiers in psychiatry · 2021
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Parallel Transmission for Ultrahigh Field MRI.Topics in magnetic resonance imaging : TMRI · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Thomas F BudingerLawrence Berkeley National Laboratory, University of California, Berkeley, CA, USA. tfbudinger@lbl.gov.
Mark D BirdNational High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, USA.
Lucio FrydmanNational High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, USA.
Joanna R LongMcKnight Brain Institute, University of Florida, Gainesville, FL, USA.
Thomas H MareciMcKnight Brain Institute, University of Florida, Gainesville, FL, USA.
William D RooneyOregon Health and Sciences University, Portland, OR, USA.
Bruce RosenMassachusetts General Hospital, Harvard Medical School, Harvard, MA, USA.
John F SchenckGeneral Electric Corporate Research, Schenectady, NY, USA.
Victor D SchepkinNational High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, USA.
A Dean SherryUniversity of Texas Southwestern Medical Center, Dallas, TX, USA.
Daniel K SodicksonSchool of Medicine, New York University, New York, NY, USA.
Charles S SpringerOregon Health and Sciences University, Portland, OR, USA.
Keith R ThulbornUniversity of Illinois, Chicago, IL, USA.
Kamil UğurbilUniversity of Minnesota, Minneapolis, MN, USA.
Lawrence L WaldMassachusetts General Hospital, Harvard Medical School, Harvard, MA, USA.

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Hersh Chandarana · 2014 to 2026
$19.3M
NIBIB NIH HHS P41 EB017183
6 · The paper itself

Abstract

An initiative to design and build magnetic resonance imaging (MRI) and spectroscopy (MRS) instruments at 14 T and beyond to 20 T has been underway since 2012. This initiative has been supported by 22 interested participants from the USA and Europe, of which 15 are authors of this review. Advances in high temperature superconductor materials, advances in cryocooling engineering, prospects for non-persistent mode stable magnets, and experiences gained from large-bore, high-field magnet engineering for the nuclear fusion endeavors support the feasibility of a human brain MRI and MRS system with 1 ppm homogeneity over at least a 16-cm diameter volume and a bore size of 68 cm. Twelve neuroscience opportunities are presented as well as an analysis of the biophysical and physiological effects to be investigated before exposing human subjects to the high fields of 14 T and beyond.

Indexed as

Magnetic Resonance ImagingAnisotropyAxonsBrainBrain MappingComputer SimulationEnergy MetabolismGlucoseHot TemperatureHumansMotionNeuronsPermeabilityReproducibility of ResultsSodium-Potassium-Exchanging ATPaseSpectrophotometryGlucoseSodium-Potassium-Exchanging ATPaseDiffusion tensor imagingHigh temperature superconductorsHuman brain chemistryMagnetic field physiologic effectsMagnetic resonance imagingParallel transmit and receive strategiesUltrahigh magnetic fields

Identifiers

PMID27194154
PMCPMC5538368

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.