Evidence map›Paper›PMID 27193721›Full record

ArticleDoklady. Biochemistry and biophysics2016

Hypoxia as pathogenic factor affecting the eye tissues: The selective apoptotic damage of the conjunctiva and anterior epithelium of the cornea.

S I Akberova, Yu V Markitantova, A A Ryabtseva, O G Stroeva

Abstract read
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In one paragraph

Article in Doklady. Biochemistry and biophysics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

S I AkberovaMedical Center "Medkvadrat,", Moscow, Russia.
Yu V MarkitantovaKoltzov Institute of Developmental Biology, Russian Academy of Sciences, ul. Vavilova 26, Moscow, 119334, Russia. yuliya.mark@gmail.com.
A A RyabtsevaMoscow Regional Clinical Research Institute (MONIKI), Moscow, Russia.
O G StroevaKoltzov Institute of Developmental Biology, Russian Academy of Sciences, ul. Vavilova 26, Moscow, 119334, Russia.
Koltzov Institute of Developmental Biology · RUMoscow Regional Scientific Research Clinical Institute. MF Vladimirsky · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of acute hypoxia on the occurrence of apoptosis in eye cells in rats placed in a pressure chamber was studied. Selective primary lesion of cells of the conjunctiva and the anterior corneal epithelium was found. A possible role of the simulated hypoxic conditions in the dry eye syndrome pathogenesis, which is accompanied by primary lesion of cells in the anterior eye surface tissues is discussed.

Indexed as

AnimalsApoptosisBenzimidazolesConjunctivaCorneaDisease Models, AnimalDNA DamageDry Eye SyndromesFluorescent DyesHypoxiaIn Situ Nick-End LabelingMaleMicroscopy, FluorescencePressureRats, WistarSeizuresBenzimidazolesbisbenzimide ethoxide trihydrochlorideFluorescent Dyes

Identifiers

PMID27193721
OpenAlexW2395523218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.