Evidence map›Paper›PMID 27193709›Full record

ArticleDoklady. Biochemistry and biophysics2016

The inhibitors of Arp2/3 complex and WASP proteins modulate the effect of glutoxim on Na(+) transport in frog skin.

Z I Krutetskaya, A V Melnitskaya, V G Antonov, A D Nozdrachev

Abstract read
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In one paragraph

Article in Doklady. Biochemistry and biophysics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Z I KrutetskayaSt. Petersburg State University, St. Petersburg State University, Universitetskaya nab. 7/9, St. Petersburg, 199034, Russia. zk@bio.spbu.ru.
A V MelnitskayaSt. Petersburg State University, St. Petersburg State University, Universitetskaya nab. 7/9, St. Petersburg, 199034, Russia.
V G AntonovSt. Petersburg State University, St. Petersburg State University, Universitetskaya nab. 7/9, St. Petersburg, 199034, Russia.
A D NozdrachevSt. Petersburg State University, St. Petersburg State University, Universitetskaya nab. 7/9, St. Petersburg, 199034, Russia.
St Petersburg University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using voltage-clamp technique, the involvement of WASP proteins and Arp2/3 complex in the effect of immunomodulator drug glutoxim on Na(+) transport in frog skin was investigated. It was shown for the first time that preincubation of the skin with the N-WASP inhibitor wiskostatin or the Arp2/3 complex inhibitor CK-0944666 significantly decreases the stimulatory effect of glutoxim on Na(+) transport. The data suggest the involvement of actin filament polymerization and branching in the glutoxim effect on Na(+) transport in frog skin.

Indexed as

Actin-Related Protein 2-3 ComplexAnimalsCarbazolesDermatologic AgentsEpithelial CellsIndolesMaleOligopeptidesPatch-Clamp TechniquesPropanolaminesRana temporariaSkinSodiumWiskott-Aldrich Syndrome ProteinActin-Related Protein 2-3 ComplexCarbazolesCK-0944666Dermatologic AgentsglutoximIndolesOligopeptidesPropanolaminesSodiumwiskostatinWiskott-Aldrich Syndrome Protein

Identifiers

PMID27193709
OpenAlexW2407445523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.