Evidence map›Paper›PMID 27193613›Full record

Trial reportEpidemiology and infection2016

Improving hand hygiene compliance in child daycare centres: a randomized controlled trial.

T P Zomer, V Erasmus, C W Looman, E F VAN Beeck, A Tjon-A-Tsien, J H Richardus, H A C M Voeten

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Epidemiology and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06736977 (Effectiveness of Nurse-Led Education Programmes to Enhance Infection Prevention and Control Among Childcare Workers in Bangkok Daycare Centres, Thailand), which is not on this map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06736977 nacompletednot on this mapstarted 2025, after this paper: background citation

Effectiveness of Nurse-Led Education Programmes to Enhance Infection Prevention and Control Among Childcare Workers in Bangkok Daycare Centres, Thailand

TypeinterventionalSponsorUniversiti Putra MalaysiaRan2025 to 2025Enrolled180ConditionsHand Hygiene Behavior, Infection Control, Infection PreventionArmsThe Onsite Nurse-Led Education Programme on IPC, The Online Nurse-Led Education Programme on IPC
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. A Systematic Review for Effective Preventive Public Education of Respiratory Infection.International journal of environmental research and public health · 2021
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

T P ZomerDepartment of Infectious Disease Control,Municipal Public Health Service Rotterdam-Rijnmond,Rotterdam,The Netherlands.
V ErasmusDepartment of Public Health,Erasmus MC,University Medical Centre Rotterdam,Rotterdam,The Netherlands.
C W LoomanDepartment of Public Health,Erasmus MC,University Medical Centre Rotterdam,Rotterdam,The Netherlands.
E F VAN BeeckDepartment of Public Health,Erasmus MC,University Medical Centre Rotterdam,Rotterdam,The Netherlands.
A Tjon-A-TsienDepartment of Infectious Disease Control,Municipal Public Health Service Rotterdam-Rijnmond,Rotterdam,The Netherlands.
J H RichardusDepartment of Infectious Disease Control,Municipal Public Health Service Rotterdam-Rijnmond,Rotterdam,The Netherlands.
H A C M VoetenDepartment of Infectious Disease Control,Municipal Public Health Service Rotterdam-Rijnmond,Rotterdam,The Netherlands.

Funding

NCATS NIH HHS L30 TR003000
6 · The paper itself

Abstract

Gastrointestinal and respiratory infections in children attending daycare centres (DCCs) are common and compliance with hand hygiene (HH) guidelines to prevent infections is generally low. An intervention was developed to increase HH compliance and reduce infections in DCCs. The objective of this paper was to evaluate the effectiveness of this intervention on HH compliance. The intervention was evaluated in a two-arm cluster randomized controlled trial in 71 DCCs in The Netherlands. Thirty-six DCCs received the intervention including: (1) HH products; (2) training about HH guidelines; (3) two team training sessions aimed at goal setting and formulating HH improvement activities; and (4) reminders and cues for action (posters/stickers). Intervention DCCs were compared to 35 control DCCs that continued usual practice. HH compliance of caregivers and children was observed at baseline and at 1, 3 and 6 months follow-up. Using multilevel logistic regression, odds ratios (ORs) with 95% confidence intervals (CIs) were obtained for the intervention effect. Of 795 caregivers, 5042 HH opportunities for caregivers and 5606 opportunities for supervising children's HH were observed. At 1 month follow-up caregivers' compliance in intervention DCCs was 66% vs. 43% in control DCCs (OR 6·33, 95% CI 3·71-10·80), and at 6 months 59% vs. 44% (OR 4·13, 95% CI 2·33-7·32). No effect of the intervention was found on supervising children's HH (36% vs. 32%; OR 0·64, 95% CI 0·18-2·33). In conclusion, HH compliance of caregivers increased due to the intervention, therefore dissemination of the intervention can be considered.

Indexed as

Guideline AdherenceHand HygieneCaregiversChild Day Care CentersChild, PreschoolGastrointestinal DiseasesHumansInfantInfant, NewbornLogistic ModelsNetherlandsRespiratory Tract InfectionsChild daycareguidelineshand hygieneinfectious disease controlintervention

Identifiers

PMID27193613
PMCPMC4988269

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.