Evidence map›Paper›PMID 27193238›Full record

ArticleParasitology research2016

Effects of Enterococcus faecalis CECT 7121 on Cryptosporidium parvum infection in mice.

Valeria F Del Coco, Mónica D Sparo, Alicia Sidoti, Mónica Santín, Juan Angel Basualdo, María Alejandra Córdoba

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Parasitology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Frontiers in microbiology · 2025
    Pooled it
  2. Article
  3. Probiotics: an alternative anti-parasite therapy.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Review
  4. Microorganisms · 2024
    Review
  5. Article
  6. Diagnosis and control of cryptosporidiosis in farm animals.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Review
  7. Effect of Caging onMicroorganisms · 2022
    Article
  8. Causes of neonatal calf diarrhea and mortality in pasture-based dairy herds in Uruguay: a farm-matched case-control study.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  9. Article
  10. Review
  11. Article
  12. Probiotics for the Control of Helminth Zoonosis.Journal of veterinary medicine · 2018
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Valeria F Del CocoCentro de Estudios Microbiológicos y Parasitológicos (CUDEMyP), Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 60 y 120, La Plata, 1900, Argentina. valeriadelcoco@med.unlp.edu.ar.
Mónica D SparoCentro de Estudios Microbiológicos y Parasitológicos (CUDEMyP), Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 60 y 120, La Plata, 1900, Argentina.
Alicia SidotiCátedra de Patología B, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina.
Mónica SantínEnvironmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, United States Department of Agriculture, Beltsville, MD, USA.
Juan Angel BasualdoCentro de Estudios Microbiológicos y Parasitológicos (CUDEMyP), Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 60 y 120, La Plata, 1900, Argentina.
María Alejandra CórdobaCentro de Estudios Microbiológicos y Parasitológicos (CUDEMyP), Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 60 y 120, La Plata, 1900, Argentina.
Universidad Nacional de La Plata · ARBeltsville Agricultural Research Center · USComisión de Investigaciones Científicas · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptosporidium is an opportunistic protozoan parasite of humans and animals worldwide and causes diarrheal disease that is typically self-limiting in immunocompetent hosts but often life threatening to immunocompromised individuals. However, there is a lack of completely efficient therapy available. Probiotics have attracted the attention as potential antiparasite compounds against protozoa involved in intestinal infections. This study investigated the effects of administration of probiotic Enterococcus faecalis CECT 7121 on Cryptosporidium parvum infection in immunosuppressed mice. Effects on C. parvum infection at the intestinal mucosa were studied and scored at each portion of the gut. It was demonstrated that Ef CECT 7121 interfered with C. parvum infection when both probiotic and parasite were present in the same intestinal location suggesting that Ef CECT 7121 supplementation can alleviate the negative effects of C. parvum infection.

Indexed as

AnimalsAntiparasitic AgentsCryptosporidiosisCryptosporidium parvumDisease Models, AnimalEnterococcus faecalisHumansImmunocompromised HostIntestinal MucosaMiceProbioticsAntiparasitic AgentsCryptosporidiumEnterococcus faecalis CECT7121Immunosuppressed miceProbiotics

Identifiers

PMID27193238
OpenAlexW2464358465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.