Evidence map›Paper›PMID 27193212›Full record

ArticleScandinavian journal of trauma, resuscitation and emergency medicine2016

Out-of-hospital cardiac arrest patients treated with cardiopulmonary resuscitation using extracorporeal membrane oxygenation: focus on survival rate and neurologic outcome.

Jae Jun Lee, Sang Jin Han, Hyoung Soo Kim, Kyung Soon Hong, Hyun Hee Choi, Kyu Tae Park, Jeong Yeol Seo, Tae Hun Lee, Heung Cheol Kim, Seonju Kim and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scandinavian journal of trauma, resuscitation and emergency medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06608095 (A Multicenter, Single-Blind Randomized Controlled Trial of TTM), which is not on this map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06608095 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

A Multicenter, Single-Blind Randomized Controlled Trial of TTM(Target Temperature Management) in Adults With ECPR(Extracorporeal Cardiopulmonary Resuscitation)

TypeinterventionalSponsorPeking University Third HospitalRan2023 to 2026Enrolled146ConditionsCardiac ArrestArmshypothermia group, normothermia group
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  10. ECPR-extracorporeal cardiopulmonary resuscitation.Indian journal of thoracic and cardiovascular surgery · 2021
    Article
  11. Extracorporeal cardiopulmonary resuscitation for adults with shock-refractory cardiac arrest.Journal of the American College of Emergency Physicians open · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jae Jun LeeDepartment of Anesthesiology, Hallym University Medical Center, Chuncheon, South Korea.
Sang Jin HanDivision of Cardiology, Department of Internal Medicine, Hallym University Medical Center, Chuncheon, South Korea.
Hyoung Soo KimDepartment of Thoracic and Cardiovascular Surgery, Hallym University Medical Center Sacred Heart Hospital, 22 Gwanpyeong-ro 170 beon-gil, Dongan-gu, Anyang-si, Gyeonggi-do, 431-070, South Korea. cskhs99@hallym.or.kr.
Kyung Soon HongDivision of Cardiology, Department of Internal Medicine, Hallym University Medical Center, Chuncheon, South Korea.
Hyun Hee ChoiDivision of Cardiology, Department of Internal Medicine, Hallym University Medical Center, Chuncheon, South Korea.
Kyu Tae ParkDivision of Cardiology, Department of Internal Medicine, Hallym University Medical Center, Chuncheon, South Korea.
Jeong Yeol SeoDepartment of Emergency Medicine, Hallym University Medical Center, Chuncheon, South Korea.
Tae Hun LeeDepartment of Emergency Medicine, Hallym University Medical Center, Chuncheon, South Korea.
Heung Cheol KimDepartment of Radiology, Hallym University Medical Center, Chuncheon, South Korea.
Seonju KimDepartment of Anesthesiology, Hallym University Medical Center, Chuncheon, South Korea.
Sun Hee LeeDepartment of Thoracic and Cardiovascular Surgery, Hallym University Medical Center Sacred Heart Hospital, 22 Gwanpyeong-ro 170 beon-gil, Dongan-gu, Anyang-si, Gyeonggi-do, 431-070, South Korea.
Sung Mi HwangDepartment of Anesthesiology, Hallym University Medical Center, Chuncheon, South Korea.
Sang Ook HaDepartment of Emergency Medicine, Hallym University Medical Center, Chuncheon, South Korea.
Hallym University Medical Center · KRHallym University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtracorporeal membrane oxygenation (ECMO) is a useful treatment for refractory out-of-hospital cardiac arrest (OHCA). However, little is known about the predictors of survival and neurologic outcome after ECMO. We analyzed our institution's experience with ECMO for refractory OHCA and evaluated the predictors of survival and neurologic outcome after ECMO.

methodsThis was a retrospective review of the medical records of 23 patients who were treated with ECMO due to OHCA that was unresponsive to conventional cardiopulmonary resuscitation, between January 2009 and January 2014.

resultsOur ECMO team was activated within 10 min for refractory OHCA, and the 30-day survival rate was 43.5 %. In a multivariate analysis that evaluated independent factors contributing to mortality, urine output  ≤ 0.5 mL · kg(-1) · h(-1) (defined as oliguria) during the 24 h after ECMO was statistically significant (OR, 32.271; 95 % CI, 1.379-755.282; p = 0.031). Just after ECMO implantation, 6 of the 9 patients (66.7 %) who had normal findings on brain computed tomography (CT) survived with a cerebral performance category (CPC) of grade 1. However, only 3 of the 11 patients (27 %) who had evidence of hypoxic brain damage on initial brain CT survived (their CPC grade was 4).

conclusionsBased on our findings, the survival rate can be improved by rapid implantation of ECMO, and oliguria seen during the first 24 h after ECMO may be an independent predictor of mortality. Furthermore, findings on brain CT just after ECMO and subsequent images may represent an important predictor for neurologic outcome after ECMO.

Indexed as

AdultAgedCardiopulmonary ResuscitationExtracorporeal Membrane OxygenationFemaleHumansHypoxia, BrainIncidenceMaleMiddle AgedOut-of-Hospital Cardiac ArrestRepublic of KoreaRetrospective StudiesSurvival RateTreatment OutcomeExtracorporeal membrane oxygenationNeurologic outcomeOliguriaOut-of-hospital cardiac arrestSurvival rate

Identifiers

PMID27193212
PMCPMC4870801
OpenAlexW2400331869

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.