ArticleScientific reports2016
Changes in profile of lipids and adipokines in patients with newly diagnosed hypothyroidism and hyperthyroidism.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Association between circulating resistin levels and thyroid dysfunction: A systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Effect of iodine nutrition on blood glucose and blood lipid levels in different regions: Based on quantile regression.PloS one · 2026Article
- Clinical Course and Risk Factors of Lenvatinib-Related Hypothyroidism in Hepatocellular Carcinoma: A Retrospective Cohort Study.Cancer reports (Hoboken, N.J.) · 2026Article
- Clinical and metabolic links between hypothyroidism and metabolic syndrome: a review.Frontiers in endocrinology · 2026Review
- Cardiovascular risk factors in autoimmune thyroiditis: role of adiponectin, resistin, inflammation and auto-immunity - a cross-sectional study.Frontiers in endocrinology · 2026Article
- Analysis of vitamin D nutritional status and disease risk factors in patients with subacute thyroiditis.Therapeutic advances in endocrinology and metabolism · 2025Article
- Gestational diabetes: a contributor to long-term thyroid dysfunction and disease.Frontiers in endocrinology · 2025Article
- Zinc and Ferritin Levels and Their Associations with Functional Disorders and/or Thyroid Autoimmunity: A Population-Based Case-Control Study.International journal of molecular sciences · 2024Article
- The Effects of Anti-thyroid Drugs on Lipoproteins and Insulin Resistance in Graves' Disease: A Randomized Clinical Trial.Journal of lipid and atherosclerosis · 2024Article
- Prognostic role and relationship of thyroid dysfunction and lipid profile in hospitalized heart failure patients.Clinical cardiology · 2023Article
- ACOX-driven peroxisomal heterogeneity and functional compartmentalization in brown adipocytes of hypothyroid rats.Royal Society open science · 2023Article
- Assessment of Metabolic Parameters in Female Triathletes with Hashimoto's Thyroiditis in Poland.Biomedicines · 2023Article
- Insulin resistance, leptin and adiponectin in lean and hypothyroid children and adolescents with obesity.BMC pediatrics · 2022Article
- The pathophysiological mechanism between hypopituitarism and nonalcoholic fatty liver disease.iLIVER · 2022Review
- Update on dyslipidemia in hypothyroidism: the mechanism of dyslipidemia in hypothyroidism.Endocrine connections · 2022Review
- Menopausal Impact on the Association Between Thyroid Dysfunction and Lipid Profiles: A Cross-Sectional Study.Frontiers in endocrinology · 2022Article
- The Aging Features of Thyrotoxicosis Mice: Malnutrition, Immunosenescence and Lipotoxicity.Frontiers in immunology · 2022Article
- Article
- Alterations of Serum Leptin Levels in Patients with Autoimmune Thyroid Disorders.Medical journal of the Islamic Republic of Iran · 2021Article
- Apolipoprotein B gene mutation related to familial hypercholesterolemia in an Iranian population: With or without hypothyroidism.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Changes in profile of lipids and adipokines have been reported in patients with thyroid dysfunction. But the evidence is controversial. The present study aimed to explore the relationships between thyroid function and the profile of lipids and adipokines. A cross-sectional study was conducted in 197 newly diagnosed hypothyroid patients, 230 newly diagnosed hyperthyroid patients and 355 control subjects. Hypothyroid patients presented with significantly higher serum levels of total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDLC), fasting insulin, resistin and leptin than control (p < 0.05). Hyperthyroid patients presented with significantly lower serum levels of high-density lipoprotein cholesterol, LDLC and leptin, as well as higher levels of fasting insulin, resistin, adiponectin and homeostasis model insulin resistance index (HOMA-IR) than control (p < 0.05). Nonlinear regression and multivariable linear regression models all showed significant associations of resistin or adiponectin with free thyroxine and association of leptin with thyroid-stimulating hormone (p < 0.001). Furthermore, significant correlation between resistin and HOMA-IR was observed in the patients (p < 0.001). Thus, thyroid dysfunction affects the profile of lipids and adipokines. Resistin may serve as a link between thyroid dysfunction and insulin resistance.
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