ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2016
Chia Seed Shows Good Protein Quality, Hypoglycemic Effect and Improves the Lipid Profile and Liver and Intestinal Morphology of Wistar Rats.
Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 88 citations in OpenAlex.
- Effects of Different Dietary Levels of Chia (Food science & nutrition · 2026Article
- Processed Pearl Millet Improves the Morphology and Gut Microbiota in Wistar Rats.Foods (Basel, Switzerland) · 2025Article
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- Evaluation of hematoprotective, hepatoprotective, and anti-inflammatory potentials of chia seed (Veterinary and animal science · 2024Article
- Investigating the Chemical Composition ofFoods (Basel, Switzerland) · 2023Article
- Intra-Amniotic Administration of Cashew Nut (Nutrients · 2023Article
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- Comparative Analysis of Metabolic Variations, Antioxidant Profiles and Antimicrobial Activity ofMolecules (Basel, Switzerland) · 2023Article
- Effect of chia flour associated with high fat diet on intestinal health in female ovariectomized Wistar rats.European journal of nutrition · 2023Article
- Sorghum flour BRS 305 hybrid has the potential to modulate the intestinal microbiota of rats fed with a high-fat high-fructose diet.European journal of nutrition · 2023Article
- UPLC-ESI-MS/MS Profiling and Cytotoxic, Antioxidant, Anti-Inflammatory, Antidiabetic, and Antiobesity Activities of the Non-Polar Fractions ofPlants (Basel, Switzerland) · 2023Article
- Comprehensive Chemical Characterization of Chia (Foods (Basel, Switzerland) · 2022Article
- Profiling of Lipids, Nutraceuticals, and Bioactive Compounds Extracted from an Oilseed Rich in PUFA.Plant foods for human nutrition (Dordrecht, Netherlands) · 2022Article
- The Current State of Knowledge onMolecules (Basel, Switzerland) · 2022Review
- Biological Potential and Chemical Profile of European Varieties ofFoods (Basel, Switzerland) · 2021Article
- Encapsulation of chia seed oil with curcumin and investigation of release behaivour & antioxidant properties of microcapsules duringLebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire · 2020Article
- Soluble Extracts from Chia Seed (Nutrients · 2019Article
- The Chemical Composition and Nutritional Value of Chia Seeds-Current State of Knowledge.Nutrients · 2019Review
- Lipoprotein Profile in Aged Rats Fed Chia Oil- or Hydroxytyrosol-Enriched Pork in High Cholesterol/High Saturated Fat Diets.Nutrients · 2018Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chia has been consumed by the world population due to its high fiber, lipids and proteins content. The objective was to evaluate the protein quality of chia untreated (seed and flour) and heat treated (90 °C/20 min), their influence on glucose and lipid homeostasis and integrity of liver and intestinal morphology of Wistar rats. 36 male rats, weanling, divided into six groups which received control diet (casein), free protein diet (aproteic) and four diet tests (chia seed; chia seed with heat treatment; chia flour and chia flour with heat treatment) for 14 days were used. The protein efficiency ratio (PER), net protein ratio (NPR) and true digestibility (TD) were evaluated. The biochemical variables and liver and intestinal morphologies of animals were determined. The values of PER, NPR and TD did not differ among the animals that were fed with chia and were lower than the control group. The animals that were fed with chia showed lower concentrations of glucose; triacylglycerides, low-density lipoprotein cholesterol and very low-density lipoprotein and higher high-density lipoprotein cholesterol than the control group. The liver weight of animals that were fed with chia was lower than the control group. Crypt depth and thickness of intestinal muscle layers were higher in groups that were fed with chia. The consumption of chia has shown good digestibility, hypoglycemic effect, improved lipid and glycemic profiles and reduced fat deposition in liver of animals, and also promoted changes in intestinal tissue that enhanced its functionality.
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