ArticleScientific reports2016
Evolving Trends in Female to Male Incidence and Male Mortality of Primary Biliary Cholangitis.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
87 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- The Epidemiology of Primary Biliary Cholangitis in European Countries: A Systematic Review and Meta-Analysis.Canadian journal of gastroenterology & hepatology · 2021Pooled it
- Trial
- An online mind-body program improves mental health and quality of life in primary biliary cholangitis: A randomized controlled trial.Hepatology communications · 2023Trial
- Geoepidemiology of Primary Biliary Cholangitis: Lessons from Switzerland.Clinical reviews in allergy & immunology · 2018Trial
- Temporal trends in the epidemiology of primary biliary cholangitis in the public healthcare system of Brazil: a large population-based study.Lancet regional health. Americas · 2026Article
- Sex and racial disparities in clinical outcomes and health resource use among patients with primary biliary cholangitis in the United States.Hepatology communications · 2026Observational
- Primary biliary cholangitis mortality in Europe: a temporal and spatial view across the period 2002-2022.BMC public health · 2026Article
- Optimizing Care in Primary Biliary Cholangitis: Current Treatments and the Second-Line Decision.Digestive diseases and sciences · 2026Review
- The impact of male sex on outcomes in primary biliary cholangitis.Scientific reports · 2026Article
- Up to 1 in 4 Veterans With Primary Biliary Cholangitis May Have Cirrhosis by the Time of Its Diagnosis.Gastro hep advances · 2026Article
- The Personalized Management of Primary Biliary Cholangitis in the Era of Precision Medicine: Current Challenges and Future Perspectives.Journal of personalized medicine · 2025Review
- Emerging Trends in Patients Hospitalised With Cirrhosis-Aetiologies, Complications and Outcomes Compared to Other Chronic Health Conditions.Alimentary pharmacology & therapeutics · 2025Article
- Epidemiology, comorbidities, treatments and outcomes of autoimmune liver diseases: A French nationwide study.JHEP reports : innovation in hepatology · 2025Article
- Triple Threat: The Importance of Diagnosing "Triple-Negative" Primary Biliary Cholangitis.Digestive diseases and sciences · 2025Article
- Primary Biliary Cholangitis: Novel and Emerging Therapies.Gastroenterology & hepatology · 2025Article
- Review
- Efficacy and Safety of Novel Oral Anti-Cholestatic Agents for Primary Biliary Cholangitis: Meta-Analyses and Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Iqirvo for primary biliary cholangitis - efficacy, safety, and future directions.Annals of medicine and surgery (2012) · 2025Review
- A nationwide study of primary biliary cholangitis prevalence, geographic distribution, and health care providers.Hepatology communications · 2025Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary biliary cholangitis (PBC) has been regarded as female-predominant without evidence of gender difference in survival. We aimed to compare the overall survival, incidence and prevalence of PBC in two well defined population-based studies over a recent decade, considering also sex ratios and mortality. We have taken advantage of population-wide records, during 2000-2009, in Lombardia, Northern Italy, and Denmark. We focused on the incident cases of PBC, including gender and outcome, among 9.7 million inhabitants of Lombardia and 5.5 million of Denmark. In Lombardia there were 2,970 PBC cases with a female:male ratio of 2.3:1. The age/sex-adjusted annual incidence of PBC was 16.7 per million. Point prevalence was 160 per million on January 1(st) 2009. In Denmark there were 722 cases of incident PBC, female:male ratio was 4.2:1, and the annual incidence was 11.4 per million, a point prevalence of 115 per million in 2009. Cox regression multivariate analysis identified male sex as an independent predictor of all-cause mortality in both Italian (HR 2.36) and Danish population (HR 3.04). Our data indicate for PBC a sex ratio significantly lower than previously cited, a reversal of the usual latitudinal difference in prevalence and a surprisingly higher overall mortality for male patients.
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