ReviewAnais brasileiros de dermatologia2016
Leprosy among children under 15 years of age: literature review.
Review in Anais brasileiros de dermatologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Osteomyelitis variolosa, an issue inherited from the past: case report and systematic review.Orphanet journal of rare diseases · 2021Pooled it
- "Reactions in Leprosy: Updated Insights Into Pathophysiology, Clinical Spectrum, and Therapeutic Approaches-A Narrative Review".Health science reports · 2026Article
- An Infectious Disease Mimicking Rheumatologic Disease in an Adolescent.Clinical pediatrics · 2025Article
- Case Report: A case of borderline lepromatous leprosy and literature review-key clues to expand clinical diagnostic thinking.Frontiers in medicine · 2025Article
- Surgery for ulnar nerve decompression and drainage of a caseous granuloma in a neural form of leprosy in children.Clinical case reports · 2023Article
- Epidemiological scenario of leprosy in marginalized communities of India: Focus on scheduled tribes.The Indian journal of medical research · 2022Review
- Impact of the COVID-19 pandemic on the diagnosis of leprosy in Brazil: An ecological and population-based study.Lancet regional health. Americas · 2022Article
- Pediatric Leprosy Profile in the Postelimination Era: A Study from Surabaya, Indonesia.The American journal of tropical medicine and hygiene · 2022Article
- Silent peripheral neuropathy determined by high-resolution ultrasound among contacts of patients with Hansen's disease.Frontiers in medicine · 2022Article
- Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management.Journal of tropical medicine · 2022Review
- [Epidemiological behavior of leprosy in several Latin American countries, 2011-2020Comportamento epidemiológico da hanseníase em vários países da América Latina, 2011-2020].Revista panamericana de salud publica = Pan American journal of public health · 2022Article
- A 5-year evaluation of chemoprophylactic treatment in elementary school children with subclinical leprosy.Biomedical reports · 2021Article
- Leprosy in children in Cuba: Epidemiological and clinical description of 50 cases from 2012-2019.PLoS neglected tropical diseases · 2021Article
- The state of the leprosy epidemic in Yunnan, China 2011-2020: A spatial and spatiotemporal analysis, highlighting areas for intervention.PLoS neglected tropical diseases · 2021Article
- Detection of Mycobacterium leprae DNA in clinical and environmental samples using serological analysis and PCR.Molecular biology reports · 2021Article
- Profiles of Pediatric Leprosy: A Report from a University Hospital of Nepal in the Post-Elimination Era.The American journal of tropical medicine and hygiene · 2021Article
- Epidemiological characteristics and trends of leprosy in children and adolescents under 15 years old in a low-endemic State in Southern Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2021Observational
- Correlation Analysis between Household Hygiene and Sanitation and Nutritional Status and Female Leprosy in Gresik Regency.Dermatology research and practice · 2020Article
- Trend analysis of leprosy indicators in a hyperendemic Brazilian state, 2001-2015.Revista de saude publica · 2019Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leprosy is a chronic infectious disease caused by Mycobacterium leprae, representing a public health issue in some countries. Though more prevalent in adults, the detection of new cases in children under 15 years of age reveals an active circulation of bacillus, continued transmission and lack of disease control by the health system, as well as aiding in the monitoring of the endemic. Among patients under 15 years of age, the most affected age group is children between 10 and 14 years of age, although cases of patients of younger than 1 year of age have also been reported. Household contacts are the primary source of infection, given that caretakers, such as babysitters and others, must be considered in this scenario. Paucibacillary forms of the disease prevailed, especially borderline-tuberculoid leprosy, with a single lesion in exposed areas of the body representing the main clinical manifestation. Reactional states: Lepra reactions are rare, although some authors have reported high frequencies of this phenomenon, the most frequent of which is Type 1 Lepra Reaction. Peripheral nerve involvement has been described at alarming rates in some studies, which increases the chance of deformities, a serious problem, especially if one considers the age of these patients. The protective effect of BCG vaccination was found in some studies, but no consensus has been reached among different authors. Children must receive the same multidrug therapy regimen and the doses should, ideally, be calculated based on the child´s weight. Adverse reactions to this therapy are rare within this age group. This article aims to review epidemiological, clinical, and therapeutic aspects of leprosy in patients under 15 years of age.
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