ArticleEmerging infectious diseases2016
High MICs for Vancomycin and Daptomycin and Complicated Catheter-Related Bloodstream Infections with Methicillin-Sensitive Staphylococcus aureus.
Article in Emerging infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Effect of the vancomycin minimum inhibitory concentration on clinical outcomes in patients with methicillin-susceptibleBMJ open · 2021Pooled it
- Dysfunctional accessory gene regulator (agr) as a prognostic factor in invasive Staphylococcus aureus infection: a systematic review and meta-analysis.Scientific reports · 2020Pooled it
- Antimicrobial activity and toxicological evaluation of didecyldimethyl-ammonium chloride complexed with fatty alcohol ethoxylate.Veterinary world · 2026Article
- Detection of septic metastases in catheter-related Staphylococcus aureus bacteremia using 18BMC infectious diseases · 2025Article
- Electrospinning of Poly-3-Hydroxybutyrate Fibers Loaded with Chlorophyll for Antibacterial Purposes.Polymers · 2024Article
- Clinical and prognostic differences between methicillin-resistant and methicillin-susceptible Staphylococcus aureus infective endocarditis.BMC infectious diseases · 2020Article
- The Cefazolin Inoculum Effect and the Presence of type AInfection & chemotherapy · 2019Article
- Sub-inhibitory concentrations of oxacillin modify the expression of agr locus in Staphylococcus aureus clinical strains belonging to different clonal complexes.BMC infectious diseases · 2018Article
- Morbidity from in-hospital complications is greater than treatment failure in patients with Staphylococcus aureus bacteraemia.BMC infectious diseases · 2018Article
- Molecular Epidemiology ofFrontiers in microbiology · 2018Article
- Pathogen-related factors affecting outcome of catheter-related bacteremia due to methicillin-susceptible Staphylococcus aureus in a Spanish multicenter study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Observational
- A 5-year Survey Reveals Increased Susceptibility to Glycopeptides for Methicillin-ResistantFrontiers in microbiology · 2017Article
- Pathogenic Characteristics ofFrontiers in microbiology · 2017Article
- Intravenous Vancomycin Dosing in the Elderly: A Focus on Clinical Issues and Practical Application.Drugs & aging · 2016Review
- Recent pattern of antibiotic resistance inJournal of laboratory physiciansArticle
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Authors and funding
18 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the prognostic role of high MICs for antistaphylococcal agents in patients with methicillin-sensitive Staphylococcus aureus catheter-related bloodstream infection (MSSA CRBSI). We prospectively reviewed 83 episodes from 5 centers in Spain during April 2011-June 2014 that had optimized clinical management and analyzed the relationship between E-test MICs for vancomycin, daptomycin, oxacillin, and linezolid and development of complicated bacteremia by using multivariate analysis. Complicated MSSA CRBSI occurred in 26 (31.3%) patients; MICs for vancomycin and daptomycin were higher in these patients (optimal cutoff values for predictive accuracy = 1.5 μg/mL and 0.5 μg/mL). High MICs for vancomycin (hazard ratio 2.4, 95% CI 1.2-5.5) and daptomycin (hazard ratio 2.4, 95% CI 1.1-5.9) were independent risk factors for development of complicated MSSA CRBSI. Our data suggest that patients with MSSA CRBSI caused by strains that have high MICs for vancomycin or daptomycin are at increased risk for complications.
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