ArticlePloS one2016
Novel Mutations in the Voltage-Gated Sodium Channel of Pyrethroid-Resistant Varroa destructor Populations from the Southeastern USA.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 105 citations in OpenAlex.
- Drugs and products in beekeeping: Efficacy and perspectives of natural alternatives.Veterinarni medicina · 2026Review
- Widespread pyrethroid resistance in Varroa destructor in Türkiye: a molecular warning.Experimental & applied acarology · 2026Article
- Evaluation of Combined Use of Protein and Postbiotics Feed Supplements in Honey Beehives in Autumn and Spring.Probiotics and antimicrobial proteins · 2025Article
- Article
- Sensitivity and Resistance of Parasitic Mites (Insects · 2025Review
- The status of pyrethroid resistance mutation frequencies in Varroa destructor populations in the most important beekeeping areas of Türkiye.Experimental & applied acarology · 2025Article
- Arising amitraz and pyrethroids resistance mutations in the ectoparasitic Varroa destructor mite in Canada.Scientific reports · 2025Article
- Population Dynamics of the MiteInsects · 2024Article
- Investigation of resistance against to flumethrin using against Varroa destructor in Türkiye.Veterinary research communications · 2024Article
- Amitraz Resistance in FrenchInsects · 2024Article
- Geographical distribution of pyrethroid resistance mutations in Varroa destructor across Türkiye and a European overview.Experimental & applied acarology · 2024Article
- Article
- Article
- Oxalic acid application method and treatment intervals for reduction of Varroa destructor (Mesostigmata: Varroidae) populations in Apis mellifera (Hymenoptera: Apidae) colonies.Journal of insect science (Online) · 2023Article
- Inducing a summer brood break increases the efficacy of oxalic acid vaporization for Varroa destructor (Mesostigmata: Varroidae) control in Apis mellifera (Hymenoptera: Apidae) colonies.Journal of insect science (Online) · 2023Article
- Varroa destructor resistance to tau-fluvalinate: relationship between in vitro phenotypic test and VGSC L925V mutation.Pest management science · 2022Article
- Article
- Trans-driven variation in expression is common among detoxification genes in the extreme generalist herbivore Tetranychus urticae.PLoS genetics · 2022Article
- Article
- Contact varroacidal efficacy of lithium citrate and its influence on viral loads, immune parameters and oxidative stress of honey bees in a field experiment.Frontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 4 countries.
Funding
Abstract
The parasitic mite Varroa destructor has a significant worldwide impact on bee colony health. In the absence of control measures, parasitized colonies invariably collapse within 3 years. The synthetic pyrethroids tau-fluvalinate and flumethrin have proven very effective at managing this mite within apiaries, but intensive control programs based mainly on one active ingredient have led to many reports of pyrethroid resistance. In Europe, a modification of leucine to valine at position 925 (L925V) of the V. destructor voltage-gated sodium channel was correlated with resistance, the mutation being found at high frequency exclusively in hives with a recent history of pyrethroid treatment. Here, we identify two novel mutations, L925M and L925I, in tau-fluvalinate resistant V. destructor collected at seven sites across Florida and Georgia in the Southeastern region of the USA. Using a multiplexed TaqMan® allelic discrimination assay, these mutations were found to be present in 98% of the mites surviving tau-fluvalinate treatment. The mutations were also found in 45% of the non-treated mites, suggesting a high potential for resistance evolution if selection pressure is applied. The results from a more extensive monitoring programme, using the Taqman® assay described here, would clearly help beekeepers with their decision making as to when to include or exclude pyrethroid control products and thereby facilitate more effective mite management programmes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.