Evidence map›Paper›PMID 27191483›Full record

ArticleEmerging infectious diseases2016

Use of Unamplified RNA/cDNA-Hybrid Nanopore Sequencing for Rapid Detection and Characterization of RNA Viruses.

Andy Kilianski, Pierce A Roth, Alvin T Liem, Jessica M Hill, Kristen L Willis, Rebecca D Rossmaier, Andrew V Marinich, Michele N Maughan, Mark A Karavis, Jens H Kuhn and 2 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Nanopore sequencing in veterinary medicine: from concepts to clinical applications.Frontiers in cellular and infection microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Andy Kilianski
Pierce A Roth
Alvin T Liem
Jessica M Hill
Kristen L Willis
Rebecca D Rossmaier
Andrew V Marinich
Michele N Maughan
Mark A Karavis
Jens H Kuhn
Anna N Honko
C Nicole Rosenzweig

Funding

NIAID NIH HHS HHSN272200700016I
6 · The paper itself

Abstract

Nanopore sequencing, a novel genomics technology, has potential applications for routine biosurveillance, clinical diagnosis, and outbreak investigation of virus infections. Using rapid sequencing of unamplified RNA/cDNA hybrids, we identified Venezuelan equine encephalitis virus and Ebola virus in 3 hours from sample receipt to data acquisition, demonstrating a fieldable technique for RNA virus characterization.

Indexed as

DNA, ComplementaryEbolavirusEncephalitis Virus, Venezuelan EquineNanoporesNucleic Acid Amplification TechniquesRNARNA VirusesTime FactorsDNA, ComplementaryRNAEbola virusfieldable platformgenomicsnanopore sequencingRNA virussequencingVenezuelan equine encephalitis virusvirusesZika virus

Identifiers

PMID27191483
PMCPMC4982148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.