ArticleJournal of clinical and diagnostic research : JCDR2016
Comparative Evaluation of Antimicrobial Effect of Three Endodontic Sealers with and Without Antibiotics - An In-vitro Study.
Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- In Vitro Antimicrobial Effects of Endoseal MTA and AH Plus Sealers onFrontiers in dentistry · 2025Article
- To check the antibacterial efficacy againstJournal of conservative dentistry and endodontics · 2024Article
- Physical Properties, Antimicrobial Activity and In Vivo Tissue Response to Apexit Plus.Materials (Basel, Switzerland) · 2020Article
- Antibacterial Additives in Epoxy Resin-Based Root Canal Sealers: A Focused Review.Dentistry journal · 2019Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRoot canal sealers with good sealing ability and antimicrobial activity are desired to entomb the surviving microorganisms.
aimAim of the present study is to evaluate the antimicrobial effect of different sealers mixed with antibiotics. MATERIALS AND
methodsSixty extracted premolars were taken and were cut coronally & apically such that 7mm of tooth specimen was prepared. They were sterilized by autoclaving, inoculated with E.faecalis and incubated for three weeks. The specimens were divided into six groups of 10 each. Group 1 - ZnOE, Group 2 - ZnOE +TAM, Group 3 - Apexit Plus, Group 4 - Apexit Plus +TAM, Group 5 - AH Plus, Group 6 - AH Plus + TAM. Bacterial growth in the each specimen was calculated before & after sealer application and noted as initial & final colony count. Antimicrobial effect of each sealer was measured by calculating the Percentage Reduction in Colony Count (%RCC). One way analysis of variance and post hoc tests were used for statistical analysis.
resultsZnOE + TAM group showed maximum antibacterial effect among the sealers tested and AH Plus sealer showed least antimicrobial effect.
conclusionWhen the sealers were mixed with triple antibiotic mixture the antimicrobial effect was increased significantly.
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