Evidence map›Paper›PMID 27190728›Full record

ArticleCureus2016

Atypical Presentation of C. Difficile Infection: Report of a Case with Literature Review.

Salman A Khan, Arooge Towheed, Sibghat Tul Llah, Aref Bin Abdulhak, Nancy R Tilson-Mallett, Alan Salkind

Abstract readCase Reports
In one paragraph

Article in Cureus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Recognition, Diagnosis, and Treatment ofPathogens (Basel, Switzerland) · 2025
    Review
  2. Article
  3. Review
  4. Case reports in surgery · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Salman A KhanDepartment of Internal Medicine, University of Missouri-Kansas City.
Arooge TowheedDepartment of Medicine, School of Medicine, University of Missouri-Kansas City.
Sibghat Tul LlahDepartment of Medicine, School of Medicine, University of Missouri-Kansas City.
Aref Bin AbdulhakDepartment of Medicine, School of Medicine, University of Missouri-Kansas City.
Nancy R Tilson-MallettDepartment of Internal Medicine, University of Missouri-Kansas City.
Alan SalkindDepartment of Internal Medicine, University of Missouri-Kansas City.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clostridium difficile (C. difficile) is a gram-positive, obligate, anaerobic spore-forming bacillus first reported by Hall and O'Toole in 1935. It occurs mostly after antibiotic use and invariably presents with watery diarrhea. We describe an atypical presentation of C. difficile in a 64-year-old Caucasian female who presented to the our emergency department with abdominal pain, nausea, and vomiting for one day. A complete blood count revealed leukocytosis 30 x 10(9)/L and a subsequent computed tomography (CT) scan of the abdomen and the pelvis, showed fluid filled small bowel loops consistent with enteritis. Her presentation was unusual for lack of diarrhea, the hallmark of C. difficile infection. She was admitted and treated with oral vancomycin. The polymerase chain reaction (PCR) value in the stool for C. difficile was positive. The patient responded very well: her abdominal pain resolved and leukocyte count normalized after a few doses of vancomycin (125 mg po qid). The patient's progress was followed in our clinic for the last three months.

Indexed as

c.difficile enteritislack of diarrhealeukocytosis

Identifiers

PMID27190728
PMCPMC4859815

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.