ArticleCase reports in nephrology2016
Suppression of Parathyroid Hormone in a Patient with Severe Magnesium Depletion.
Article in Case reports in nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.Nutrients · 2023Pooled it
- The Clinical Spectrum of Acquired Hypomagnesemia: From Etiology to Therapeutic Approaches.Biomedicines · 2025Review
- Dramatic Deterioration of Subclinical Hyperparathyroidism in Children and Adolescents During the Post-COVID-19 Period.Diseases (Basel, Switzerland) · 2025Article
- The Importance of Vitamin D and Magnesium in Athletes.Nutrients · 2025Review
- Hypocalcaemic tetany linked to vitamin D deficiency and hypomagnesemia in primary intestinal lymphangiectasia: a literature review.Annals of medicine and surgery (2012) · 2024Review
- The role of magnesium in the pathogenesis of osteoporosis.Frontiers in endocrinology · 2024Review
- [Review of clinical practice guidelines for hypoparathyroidism].Problemy endokrinologii · 2021Review
- Vitamin D Sources, Metabolism, and Deficiency: Available Compounds and Guidelines for Its Treatment.Metabolites · 2021Review
- Magnesium in Infectious Diseases in Older People.Nutrients · 2021Review
- Concomitant Fahr's syndrome and thoracic ossification of the posterior longitudinal ligament caused by idiopathic hypoparathyroidism - case report.BMC musculoskeletal disorders · 2019Article
- Magnesemia: an independent risk factor of hypocalcemia after thyroidectomy.Cancer management and research · 2019Article
- Magnesium and Human Health: Perspectives and Research Directions.International journal of endocrinology · 2018Review
- Electrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management.Cancer chemotherapy and pharmacology · 2017Review
- Hypocalcemia in a Patient with Cancer.Clinical journal of the American Society of Nephrology : CJASN · 2017Article
- Patterns and Correlates of Serum Magnesium Levels in Subsets of Type 2 Diabetes Mellitus Patients in Nigeria.Indian journal of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypomagnesemia is often associated with coexisting electrolyte abnormalities like hypokalemia and hypocalcemia. Hypocalcemia has been shown to be secondary to hypoparathyroidism induced by hypomagnesemia. Here, we discuss a case of a patient with severe hypomagnesemia and associated hypocalcemia. A 38-year-old lady was admitted to the hospital for weakness of lower extremities and an eventual fall. The exam was significant for decreased motor strength and some paresthesias. The laboratory data was significant for hypomagnesemia, hypokalemia, and low parathyroid level in the face of hypocalcemia. After replacing magnesium, the parathyroid hormone levels normalized and led to eventual correction of calcium levels without any additional calcium replacement therapy. There was complete symptom resolution with correction of electrolyte abnormalities. This case highlights the importance of looking for all associated abnormalities in a patient with hypomagnesemia and starting the replacement therapy by first replacing the magnesium and then the others as needed. Replacing the magnesium alone may correct the hypoparathyroidism and eliminate the need for calcium replacement.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.