Evidence map›Paper›PMID 27190582›Full record

ReviewWorld journal of gastrointestinal oncology2016

Role of Raman spectroscopy and surface enhanced Raman spectroscopy in colorectal cancer.

Cerys A Jenkins, Paul D Lewis, Peter R Dunstan, Dean A Harris

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in World journal of gastrointestinal oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04040673 (Evaluation of the Role of Vibrational Spectroscopy in the Diagnosis of Premalignant and Malignant Disease of the Thyroid RAFTER), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04040673 unknown statusnot on this mapstarted 2024, after this paper: background citation

Evaluation of the Role of Vibrational Spectroscopy in the Diagnosis of Premalignant and Malignant Disease of the Thyroid RAFTER (RAman For Thyroid cancER)

TypeobservationalSponsorGloucestershire Hospitals NHS Foundation TrustRan2024 to 2025Enrolled40ConditionsThyroid Diseases, Thyroid CancerArmsthyroid lobectomy, Raman spectroscopy probe measurement
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Differential effects of sPLAMolecular and cellular biochemistry · 2018
    Article
  8. Advances in Lipidomics for Cancer Biomarkers Discovery.International journal of molecular sciences · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cerys A JenkinsCerys A Jenkins, Paul D Lewis, Dean A Harris, Swansea University Medical School, Swansea University, Swansea SA2 8PP, United Kingdom.
Paul D LewisCerys A Jenkins, Paul D Lewis, Dean A Harris, Swansea University Medical School, Swansea University, Swansea SA2 8PP, United Kingdom.
Peter R DunstanCerys A Jenkins, Paul D Lewis, Dean A Harris, Swansea University Medical School, Swansea University, Swansea SA2 8PP, United Kingdom.
Dean A HarrisCerys A Jenkins, Paul D Lewis, Dean A Harris, Swansea University Medical School, Swansea University, Swansea SA2 8PP, United Kingdom.
Swansea University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is the fourth most common cancer in the United Kingdom and is the second largest cause of cancer related death in the United Kingdom after lung cancer. Currently in the United Kingdom there is not a diagnostic test that has sufficient differentiation between patients with cancer and those without cancer so the current referral system relies on symptomatic presentation in a primary care setting. Raman spectroscopy and surface enhanced Raman spectroscopy (SERS) are forms of vibrational spectroscopy that offer a non-destructive method to gain molecular information about biological samples. The techniques offer a wide range of applications from in vivo or in vitro diagnostics using endoscopic probes, to the use of micro-spectrometers for analysis of biofluids. The techniques have the potential to detect molecular changes prior to any morphological changes occurring in the tissue and therefore could offer many possibilities to aid the detection of CRC. The purpose of this review is to look at the current state of diagnostic technology in the United Kingdom. The development of Raman spectroscopy and SERS in clinical applications relation for CRC will then be discussed. Finally, future areas of research of Raman/SERS as a clinical tool for the diagnosis of CRC are also discussed.

Indexed as

Colorectal cancerDetectionRamanSpectroscopySurface enhanced Raman spectroscopy

Identifiers

PMID27190582
PMCPMC4865710
OpenAlexW2396458219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.