Evidence map›Paper›PMID 27190580›Full record

ArticleWorld journal of hepatology2016

Direct acting antiviral therapy is curative for chronic hepatitis C/autoimmune hepatitis overlap syndrome.

Farhad Sahebjam, Cristina H Hajdu, Esther Nortey, Samuel H Sigal

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Farhad SahebjamFarhad Sahebjam, Esther Nortey, Samuel H Sigal, Division of Gastroenterology, New York University School of Medicine, New York, NY 10016, United States.
Cristina H HajduFarhad Sahebjam, Esther Nortey, Samuel H Sigal, Division of Gastroenterology, New York University School of Medicine, New York, NY 10016, United States.
Esther NorteyFarhad Sahebjam, Esther Nortey, Samuel H Sigal, Division of Gastroenterology, New York University School of Medicine, New York, NY 10016, United States.
Samuel H SigalFarhad Sahebjam, Esther Nortey, Samuel H Sigal, Division of Gastroenterology, New York University School of Medicine, New York, NY 10016, United States.
New York University · USAlbert Einstein College of Medicine · US

Funding

Special Animal CoreP30DK041296 · NIDDK · YESHIVA UNIVERSITY · PI WOLKOFF, ALLAN W · 1989 to 2018
$22.9M
NIDDK NIH HHS P30 DK041296
6 · The paper itself

Abstract

Autoimmune phenomena are common in patients with chronic hepatitis C. Management of chronic hepatitis C/autoimmune hepatitis syndrome has until recently been problematic due to the adverse effects of interferon on autoimmune processes and immunosuppression on viral replication. In this report we describe 3 patients with chronic hepatitis C/autoimmune hepatitis overlap syndrome who responded rapidly to direct acting anti-viral therapy. The resolution of the autoimmune process supports a direct viral role in its pathophysiology.

Indexed as

Autoimmune hepatitisDirect acting antiviral therapyHepatitis COverlap syndrome

Identifiers

PMID27190580
PMCPMC4867421
OpenAlexW2351142271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.