Evidence map›Paper›PMID 27190259›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2016

Glycomaterials for probing host-pathogen interactions and the immune response.

Mia L Huang, Christopher J Fisher, Kamil Godula

Open access · greenAbstract readReview
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Engineering galectin-glycan interactions for immunotherapy and immunomodulation.Experimental biology and medicine (Maywood, N.J.) · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mia L HuangDepartment of Chemistry and Biochemistry, University of California-San Diego, La Jolla, CA 92093, USA.
Christopher J FisherDepartment of Chemistry and Biochemistry, University of California-San Diego, La Jolla, CA 92093, USA.
Kamil GodulaDepartment of Chemistry and Biochemistry, University of California-San Diego, La Jolla, CA 92093, USA kgodula@ucsd.edu.
University of California, San Diego · US

Funding

MOLECULAR BIOPHYSICS TRAINING PROGRAMT32GM008326 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KOMIVES, ELIZABETH A. · 1989 to 2020
$7.5M
In vivo glycan engineering at the cell-matrix interface to control stem cell fateDP2HD087954 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GODULA, KAMIL · 2015 to 2015
$2.3M
NeoProteoglycans as synthetic materials for regenerative medicine and bioimagingR00EB013446 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GODULA, KAMIL · 2013 to 2015
$722k
NIBIB NIH HHS R00 EB013446NICHD NIH HHS DP2 HD087954NIGMS NIH HHS T32 GM008326
6 · The paper itself

Abstract

The initial engagement of host cells by pathogens is often mediated by glycan structures presented on the cell surface. Various components of the glycocalyx can be targeted by pathogens for adhesion to facilitate infection. Glycans also play integral roles in the modulation of the host immune response to infection. Therefore, understanding the parameters that define glycan interactions with both pathogens and the various components of the host immune system can aid in the development of strategies to prevent, interrupt, or manage infection. Glycomaterials provide a unique and powerful tool with which to interrogate the compositional and functional complexity of the glycocalyx. The objective of this review is to highlight some key contributions from this area of research in deciphering the mechanisms of pathogenesis and the associated host response.

Indexed as

Host-Pathogen InteractionsImmunity, InnateAnimalsHumansPolysaccharidesPolysaccharidesglycobiologyglycocalyxGlycomaterialsimmunology/microbiology/virologyimmunomodulationpathogenesis

Identifiers

PMID27190259
PMCPMC4950362
OpenAlexW2398476114

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.