ArticleGenome biology and evolution2016
Population and Evolutionary Genomics of Amblyomma americanum, an Expanding Arthropod Disease Vector.
Article in Genome biology and evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
51 citing papers in PubMed.
- Days of Future Passed: Best Calibration Does Not Guarantee Reliable Forecasts of Future Tick Distributions.Pathogens (Basel, Switzerland) · 2026Article
- Field evaluation of novel experimental nootkatone-based products for control of Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae).Journal of medical entomology · 2026Article
- Beefing Up Awareness: Navigating Alpha-Gal Syndrome.Clinical journal of oncology nursing · 2026Review
- Sexual and regional differences in the microbiome and functional metagenome of the lone star tick, Amblyomma americanum.Animal microbiome · 2025Article
- Tracking invasion events: phylogeography of Hyalomma marginatum in the Mediterranean basin with a focus on Southern France.Parasites & vectors · 2025Article
- Genome-wide insights into genetic diversity of endemic and non-endemic Ixodes ricinus populations.Scientific reports · 2025Article
- Article
- Focal persistence and phylodynamics of Heartland virus in Georgia.Virus evolution · 2025Article
- Alpha-Gal Syndrome: Often Hidden, Under-Recognized, and in Need of Attention-A Rapid Review.International journal of general medicine · 2025Review
- Impact of climate change on the tick-host-pathogen complex: distribution patterns, disease incidence, and host infestation.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2025Review
- Is dragging a drag or is trapping a trap? A comparison of two methods for collecting Amblyomma americanum ticks in sites near the species range boundary.Experimental & applied acarology · 2024Article
- Comparative speed of kill provided by lotilaner (Credelio™), sarolaner (Simparica Trio™), and afoxolaner (NexGard™) to control Amblyomma americanum infestations on dogs.Parasites & vectors · 2024Article
- Neurological manifestations of ehrlichiosis among a cohort of patients: prevalence and clinical symptoms.BMC infectious diseases · 2024Article
- Article
- Modeling Heartland virus disease in mice and therapeutic intervention with 4'-fluorouridine.Journal of virology · 2024Article
- Optimization of artificial membrane feeding system for lone star ticks, Amblyomma americanum (Acari: Ixodidae), and experimental infection with Rickettsia amblyommatis (Rickettsiales: Rickettsiaceae).Journal of medical entomology · 2024Article
- Heartland Virus Disease-An Underreported Emerging Infection.Microorganisms · 2024Review
- Article
- Tick-Borne Co-Infections: Challenges in Molecular and Serologic Diagnoses.Pathogens (Basel, Switzerland) · 2023Review
- Tick bite-induced Alpha-Gal Syndrome and Immunologic Responses in an Alpha-Gal Deficient Murine Model.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The lone star tick, Amblyomma americanum, is an important disease vector and the most frequent tick found attached to humans in the eastern United States. The lone star tick has recently experienced a rapid range expansion into the Northeast and Midwest, but despite this emerging infectious threat to wildlife, livestock, and human health, little is known about the genetic causes and consequences of the geographic expansion. In the first population genomic analysis of any tick species, we characterize the genetic diversity and population structure of A. americanum across its current geographic range, which has recently expanded. Using a high-throughput genotyping-by-sequencing approach, we discovered more than 8,000 single nucleotide polymorphisms in 90 ticks from five locations. Surprisingly, newly established populations in New York (NY) and Oklahoma (OK) are as diverse as historic range populations in North and South Carolina. However, substantial population structure occurs among regions, such that new populations in NY and OK are genetically distinct from historic range populations and from one another. Ticks from a laboratory colony are genetically distinct from wild populations, underscoring the need to account for natural variation when conducting transmission or immunological studies, many of which utilize laboratory-reared ticks. An FST-outlier analysis comparing a recently established population to a long-standing population detected numerous outlier sites, compatible with positive and balancing selection, highlighting the potential for adaptation during the range expansion. This study provides a framework for applying high-throughput DNA sequencing technologies for future investigations of ticks, which are common vectors of diseases.
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