Evidence map›Paper›PMID 27189865›Full record

ReviewThe ocular surface2016

Impact of Microbiome on Ocular Health.

Abirami Kugadas, Mihaela Gadjeva

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in The ocular surface, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04322500 (Intestinal Microbiota), which is not on this map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04322500 nacompletednot on this mapstarted 2019, after this paper: background citation

Intestinal Microbiota: a New Target for Chalaziosis Treatment in Children

TypeinterventionalSponsorUniversity of MoliseRan2019 to 2020Enrolled26ConditionsChalazionArmsprobiotics, conservative treatment
3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 158 citations in OpenAlex.

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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Abirami KugadasDepartment of Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Mihaela GadjevaDepartment of Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: mgadjeva@rics.bwh.harvard.edu.
Harvard University · US

Funding

Novel treatment strategies to regulate inflammation during P.aeruginosa keratitisR01EY022054 · NEI · BRIGHAM AND WOMEN'S HOSPITAL · PI GADJEVA, MIHAELA GUEORGUIEVA · 2012 to 2020
$4.0M
NEI NIH HHS R01 EY022054
6 · The paper itself

Abstract

The ocular surface is continuously exposed to the environment and, therefore, it is surprising that it harbors only few commensals with low degree of diversity. This unique aspect of the ocular surface physiology prompts the question whether there are core ocular commensal communities and how they affect ocular immunity. The purpose of this review is to provide an overview of what is known about the ocular surface commensals in health and disease and what we would like to learn in the near future. In addition, we discuss how microbiota at sites other than the eye may influence ocular immune responses. The information discussed in the review has been gathered using PubMed searches for literature published from January 1982 to December 2015.

Indexed as

MicrobiotaEyeHumanscontact lensesIgAmicrobiotaocular surface

Identifiers

PMID27189865
PMCPMC5082109
OpenAlexW2366175660

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.