ArticleTransfusion2016
Blood group A and D negativity are associated with symptomatic West Nile virus infection.
Article in Transfusion, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- The role of host genetics in susceptibility to severe viral infections in humans and insights into host genetics of severe COVID-19: A systematic review.Virus research · 2020Pooled it
- Seroprevalence of West Nile virus among blood donors in mainland France, 2021 to 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026Article
- West Nile Virus: Seroprevalence and Epidemiological Study in Blood Donors in North Central Anatolia Amid Global Threats.Journal of medical virology · 2026Article
- Awareness of West Nile Virus and Zoonotic Disease Transmission among Residents of Northern Cyprus: A Cross-Sectional Study.Journal of arthropod-borne diseases · 2026Article
- Analysis between ABO blood group and clinical outcomes in COVID-19 patients and the potential mediating role of ACE2.Frontiers in medicine · 2023Article
- ABO blood group and link to COVID-19: A comprehensive review of the reported associations and their possible underlying mechanisms.Microbial pathogenesis · 2022Review
- Lack of association between feline AB blood groups and retroviral status: a multicenter, multicountry study.Journal of feline medicine and surgery · 2022Article
- Emphasizing the link between blood types in multi-ethnic disparities and COVID-19 infection in Makkah, Saudi Arabia.Saudi medical journal · 2022Article
- "Mysterious veil" between the blood group system and pathogens.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Article
- Host variations in SARS-CoV-2 infection.Turkish journal of biology = Turk biyoloji dergisi · 2021Review
- Association of blood groups on the risk of COVID-19 infection, morbidity, and mortality.Northern clinics of Istanbul · 2021Article
- ABO blood group system is associated with COVID-19 mortality: An epidemiological investigation in the Indian population.Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine · 2020Article
- Relationship between ABO blood group distribution and clinical characteristics in patients with COVID-19.Clinica chimica acta; international journal of clinical chemistry · 2020Article
- Seroprevalence of hepatitis E virus among blood donors on Corsica, France, 2017.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundWest Nile virus (WNV) infection is mostly asymptomatic (AS) but 20% of subjects report WNV fever and 1% of patients experience neurologic diseases with higher rates in elderly and immunosuppressed persons. With no treatment and no vaccine to prevent the development of symptomatic (S) infections, it is essential to understand prognostic factors influencing S disease outcome. Host genetic background has been linked to the development of WNV neuroinvasive disease. This study investigates the association between the ABO and D blood group status and WNV disease outcome. STUDY DESIGN AND
methodsThe distribution of blood groups was investigated within a cohort of 374 WNV+ blood donors including 244 AS and 130 S WNV+ blood donors. Logistic regression analyses were used to examine associations between A, B, O, and D blood groups and WNV clinical disease outcome.
resultsS WNV+ donors exhibited increased frequencies of blood group A (S 47.6%, AS 36.8%, p = 0.04; odds ratio [OR], 1.56; 95% confidence interval [CI], 1.01-2.40) and D- individuals (S 21.5%, AS 13.1%, p = 0.03; OR, 1.82; 95% CI, 1.04-3.18).
conclusionThe findings suggest a genetic susceptibility placing blood group A and D- individuals at risk for the development of S disease outcome after WNV infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.