Evidence map›Paper›PMID 27189729›Full record

ArticleAge and ageing2016

Physical activity and incidence of sarcopenia: the population-based AGES-Reykjavik Study.

Donja M Mijnarends, Annemarie Koster, Jos M G A Schols, Judith M M Meijers, Ruud J G Halfens, Vilmundur Gudnason, Gudny Eiriksdottir, Kristin Siggeirsdottir, Sigurdur Sigurdsson, Pálmi V Jónsson and 2 more

Registry-linked trialOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Age and ageing, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05294380 (Determination of Sarcopenia Risk and Related Factors in Pediatric Oncological Patients), which is not on this map. Cited by 99 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 3 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05294380 unknown statusnot on this mapstarted 2021, after this paper: background citation

Determination of Sarcopenia Risk and Related Factors in Pediatric Oncological Patients

TypeobservationalSponsorTrakya UniversityRan2021 to 2022Enrolled60ConditionsSarcopenia, Pediatric Cancer
3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 3 syntheses or guidelines pooled it, 189 citations in OpenAlex.

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  10. An Ethnographic Exploration of Social-Ecological Influences on Physical Activity in Care Homes for Older People.Health expectations : an international journal of public participation in health care and health policy · 2026
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39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Donja M MijnarendsCAPHRI/Department of Health Services Research, Maastricht University, Maastricht, The Netherlands d.mijnarends@maastrichtuniversity.nl.
Annemarie KosterCAPHRI/Department of Social Medicine, Maastricht University, Maastricht, The Netherlands.
Jos M G A ScholsCAPHRI/Department of Health Services Research, Maastricht University, Maastricht, The Netherlands CAPHRI/Department of Family Medicine, Maastricht University, Maastricht, The Netherlands.
Judith M M MeijersCAPHRI/Department of Health Services Research, Maastricht University, Maastricht, The Netherlands.
Ruud J G HalfensCAPHRI/Department of Health Services Research, Maastricht University, Maastricht, The Netherlands.
Vilmundur GudnasonFaculty of Medicine, University of Iceland, Reykjavik, Iceland Icelandic Heart Association Research Institute, Kopavogur, Iceland.
Gudny EiriksdottirIcelandic Heart Association Research Institute, Kopavogur, Iceland.
Kristin SiggeirsdottirIcelandic Heart Association Research Institute, Kopavogur, Iceland.
Sigurdur SigurdssonIcelandic Heart Association Research Institute, Kopavogur, Iceland.
Pálmi V JónssonFaculty of Medicine, University of Iceland, Reykjavik, Iceland Department of Geriatrics, Landspitali National University Hospital, Reykjavik, Iceland.
Osorio MeirellesLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA.
Tamara HarrisLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA.
Maastricht University · NLIcelandic Heart Association · ISNational Institute on Aging · USUniversity of Iceland · IS

Funding

THE PURPOSE OF MODIFICATION TO(1)INCREASE EFFORT OF OPTION 2 AND OPTION 3 FOR ICN01AG12100 · NIA · ICELANDIC HEART ASSOCIATION · PI GUDNASON, VILMUNDUR · 2007 to 2012
$18.4M
AGES STUDY-THE REYKJAVIK STUDY OF HEALTHY AGING FOR THE NEW MILLENNIUM-26012100N01AG012100 · NIA · ICELANDIC HEART ASSOCIATION · 2002 to 2004
–
NIA NIH HHS N01AG12100
6 · The paper itself

Abstract

backgroundthe prevalence of sarcopenia increases with age. Physical activity might slow the rate of muscle loss and therewith the incidence of sarcopenia.

objectiveto examine the association of physical activity with incident sarcopenia over a 5-year period.

designdata from the population-based Age, Gene/Environment, Susceptibility-Reykjavik Study were used.

settingpeople residing in the Reykjavik area at the start of the study. SUBJECTS: the study included people aged 66-93 years (n = 2309).

methodsthe amount of moderate-vigorous physical activity (MVPA) was assessed by a self-reported questionnaire. Sarcopenia was identified using the European Working Group on Sarcopenia in Older People algorithm, including muscle mass (computed tomography imaging), grip strength (computerised dynamometer) and gait speed (6 m).

resultsmean age of the participants was 74.9 ± 4.7 years. The prevalence of sarcopenia was 7.3% at baseline and 16.8% at follow-up. The incidence proportion of sarcopenia over 5 years was 14.8% in the least-active individuals and 9.0% in the most-active individuals. Compared with the least-active participants, those reporting a moderate-high amount of MVPA had a significantly lower likelihood of incident sarcopenia (OR = 0.64, 95% CI 0.45-0.91). Participants with a high amount of MVPA had higher baseline levels of muscle mass, strength and walking speed, but baseline MVPA was not associated with the rate of muscle loss.

conclusiona higher amount of MVPA seems to contribute to counteracting the development of sarcopenia. To delay the onset of sarcopenia and its potential adverse outcomes, attention should be paid to increasing physical activity levels in older adults.

Indexed as

ExerciseAgedAged, 80 and overFemaleGaitHand StrengthHumansIcelandIncidenceMaleMuscle, SkeletalRisk FactorsSarcopeniaSurveys and QuestionnairesTomography, X-Ray ComputedEWGSOPincidence proportionolder peoplephysical activitysarcopenia

Identifiers

PMID27189729
PMCPMC5027639
OpenAlexW2407511756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.