ArticleMolecular biology and evolution2016
Evolutionary Metabolomics Reveals Domestication-Associated Changes in Tetraploid Wheat Kernels.
Article in Molecular biology and evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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60 citing papers in PubMed.
- Natural selection shapes the evolution of the metabolome in Saccharomyces cerevisiae.Molecular biology and evolution · 2026Article
- Integration of the D-Genome Reshapes Gene Transcription, Chromatin Architecture, and Metabolome of Allohexaploid Wheat, Leading to Enhanced Environmental Adaptability.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Metabolic reprogramming and functional trade-offs during domestication of Sechium edule.Scientific reports · 2026Article
- Genome-wide association analysis and linkage mapping decipher the genetic control of primary metabolites and quality traits in Capsicum.The Plant journal : for cell and molecular biology · 2025Article
- Enhancing wheat resilience: biotechnological advances in combating heat stress and environmental challenges.Plant molecular biology · 2025Review
- Harnessing multi-omics approaches to combat Karnal bunt of wheat: a review of advances and future prospects.Frontiers in genetics · 2025Review
- Lipidomic Profiling of Common Wheat Flours from 1891-2010.Journal of agricultural and food chemistry · 2024Article
- Evolution of plant metabolism: the state-of-the-art.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Transcriptomic response to nitrogen availability reveals signatures of adaptive plasticity during tetraploid wheat domestication.The Plant cell · 2024Article
- Lipids and Fatty Acid Composition Reveal Differences between Durum Wheat Landraces and Modern Cultivars.Plants (Basel, Switzerland) · 2024Article
- The metabolic domestication syndrome of budding yeast.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Integrating genomics and genome editing for orphan crop improvement: a bridge between orphan crops and modern agriculture system.GM crops & food · 2023Review
- Plant Metabolomics: Current Initiatives and Future Prospects.Current issues in molecular biology · 2023Review
- Principles of metabolome conservation in animals.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Symbiotic Variations among Wheat Genotypes and Detection of Quantitative Trait Loci for Molecular Interaction with Auxin-ProducingMicroorganisms · 2023Article
- A metabolic perspective of selection for fruit quality related to apple domestication and improvement.Genome biology · 2023Article
- Selection and adaptive introgression guided the complex evolutionary history of the European common bean.Nature communications · 2023Article
- Plant and microbial sciences as key drivers in the development of metabolomics research.Proceedings of the National Academy of Sciences of the United States of America · 2023Review
- Watermelon domestication was shaped by stepwise selection and regulation of the metabolome.Science China. Life sciences · 2023Article
- Targeted approaches to improve tomato fruit taste.Horticulture research · 2023Article
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11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Domestication and breeding have influenced the genetic structure of plant populations due to selection for adaptation from natural habitats to agro-ecosystems. Here, we investigate the effects of selection on the contents of 51 primary kernel metabolites and their relationships in three Triticum turgidum L. subspecies (i.e., wild emmer, emmer, durum wheat) that represent the major steps of tetraploid wheat domestication. We present a methodological pipeline to identify the signature of selection for molecular phenotypic traits (e.g., metabolites and transcripts). Following the approach, we show that a reduction in unsaturated fatty acids was associated with selection during domestication of emmer (primary domestication). We also show that changes in the amino acid content due to selection mark the domestication of durum wheat (secondary domestication). These effects were found to be partially independent of the associations that unsaturated fatty acids and amino acids have with other domestication-related kernel traits. Changes in contents of metabolites were also highlighted by alterations in the metabolic correlation networks, indicating wide metabolic restructuring due to domestication. Finally, evidence is provided that wild and exotic germplasm can have a relevant role for improvement of wheat quality and nutritional traits.
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