Evidence map›Paper›PMID 27189534›Full record

ArticleStatistics in medicine2016

Estimating the expected value of partial perfect information in health economic evaluations using integrated nested Laplace approximation.

Anna Heath, Ioanna Manolopoulou, Gianluca Baio

Abstract read
In one paragraph

Article in Statistics in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. A Pragmatic Bayesian Adaptive Trial Design Based on the Value of Information: The Value-Driven Adaptive Design.Medical decision making : an international journal of the Society for Medical Decision Making · 2026
    Article
  2. Accurate EVSI Estimation for Nonlinear Models Using the Gaussian Approximation Method.Medical decision making : an international journal of the Society for Medical Decision Making · 2024
    Article
  3. Prioritizing Research in an Era of Personalized Medicine: The Potential Value of Unexplained Heterogeneity.Medical decision making : an international journal of the Society for Medical Decision Making · 2022
    Article
  4. Value of Information Analysis in Models to Inform Health Policy.Annual review of statistics and its application · 2022
    Article
  5. Multilevel and Quasi Monte Carlo Methods for the Calculation of the Expected Value of Partial Perfect Information.Medical decision making : an international journal of the Society for Medical Decision Making · 2022
    Article
  6. Article
  7. Article
  8. Computing the Expected Value of Sample Information Efficiently: Practical Guidance and Recommendations for Four Model-Based Methods.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2020
    Article
  9. Value of Information Analytical Methods: Report 2 of the ISPOR Value of Information Analysis Emerging Good Practices Task Force.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2020
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anna HeathDepartment of Statistical Science, University College London, Department of Statistical Science, University College London, U.K.
Ioanna ManolopoulouDepartment of Statistical Science, University College London, Department of Statistical Science, University College London, U.K.
Gianluca BaioDepartment of Statistical Science, University College London, Department of Statistical Science, University College London, U.K.ORCID 0000-0003-4314-2570

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Expected Value of Perfect Partial Information (EVPPI) is a decision-theoretic measure of the 'cost' of parametric uncertainty in decision making used principally in health economic decision making. Despite this decision-theoretic grounding, the uptake of EVPPI calculations in practice has been slow. This is in part due to the prohibitive computational time required to estimate the EVPPI via Monte Carlo simulations. However, recent developments have demonstrated that the EVPPI can be estimated by non-parametric regression methods, which have significantly decreased the computation time required to approximate the EVPPI. Under certain circumstances, high-dimensional Gaussian Process (GP) regression is suggested, but this can still be prohibitively expensive. Applying fast computation methods developed in spatial statistics using Integrated Nested Laplace Approximations (INLA) and projecting from a high-dimensional into a low-dimensional input space allows us to decrease the computation time for fitting these high-dimensional GP, often substantially. We demonstrate that the EVPPI calculated using our method for GP regression is in line with the standard GP regression method and that despite the apparent methodological complexity of this new method, R functions are available in the package BCEA to implement it simply and efficiently. © 2016 The Authors. Statistics in Medicine Published by John Wiley & Sons Ltd.

Indexed as

Monte Carlo MethodUncertaintyCost-Benefit AnalysisDecision MakingHumansRegression AnalysisGaussian Process regressionHealth economic evaluationSPDE-INLAValue of information

Identifiers

PMID27189534
PMCPMC5031203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.