Evidence map›Paper›PMID 27189389›Full record

ArticleScandinavian journal of primary health care2016

No association between level of vitamin D and chronic low back pain in Swedish primary care: a cross-sectional case-control study.

Andreas Thörneby, Lena Margareta Nordeman, Else Hellebö Johanson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scandinavian journal of primary health care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  5. Article
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  8. Observational
  9. Article
  10. Is there role for vitamin D in the treatment of chronic pain?Therapeutic advances in musculoskeletal disease · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Andreas Thörnebya Department of Research and Development, Primary Health Care , Research and Development Center Södra Älvsborg, Region Västra Götaland , Borås , Sweden ;
Lena Margareta Nordemana Department of Research and Development, Primary Health Care , Research and Development Center Södra Älvsborg, Region Västra Götaland , Borås , Sweden ;
Else Hellebö Johansona Department of Research and Development, Primary Health Care , Research and Development Center Södra Älvsborg, Region Västra Götaland , Borås , Sweden ;
Region Västra Götaland · SESödra Älvsborg Hospital · SEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAssessment of vitamin D levels and deficiency status in individuals with chronic low back pain (CLBP) in a Swedish general population, compared with controls matched for sex and age.

designCross-sectional case-control study.

settingPrimary care, southern Sweden. SUBJECTS: Participants (n = 44) with self-reported low back pain for at least 3 months and individually sex- and age-matched controls without a chronic pain condition (n = 44), recruited from the general population by random letter of invitation.

main outcome measureAssociation between vitamin D level and CLBP when adjusting for possible confounders in a multivariate forward conditional logistic regression model.

resultsMean S-25-hydroxyvitamin D levels were 81 and 80 nmol/L in the CLBP and control group, respectively. The prevalence of vitamin D deficiency was low and similar in the CLBP group and the control group. Vitamin D level was not associated with CLBP when potential confounders were taken into account.

conclusionsNo difference in vitamin D levels between participants with CLBP and matched controls could be demonstrated in the present sample. Assessment of vitamin D level and deficiency status may be of questionable value in the management of CLBP in primary care settings at similar latitudes, unless there are additional risk factors for deficiency or specific indicators of osteomalacia. Key points Vitamin D deficiency is common and reported in many chronic pain conditions, including chronic low back pain (CLBP), but evidence for an association and causality is insufficient. • The present study found no association between vitamin D levels and CLBP in a case-control sample of 44 + 44 individuals from the Swedish general population. • Prevalence of vitamin D deficiency was low and comparable in individuals with CLBP and controls without chronic pain, matched for sex and age. • Assessment of vitamin D status, for the purpose of finding and treating an underlying cause of pain, may be of limited value in the management of CLBP in primary care settings at similar latitudes.

Indexed as

AdultAgedBiomarkersCase-Control StudiesChronic PainCross-Sectional StudiesFemaleHumansLogistic ModelsLow Back PainMaleMiddle AgedRisk FactorsSwedenVitamin DVitamin D Deficiency25-hydroxyvitamin DBiomarkersVitamin DChronic paingeneral practicelow back painprimary health careSwedenvitamin D

Identifiers

PMID27189389
PMCPMC4977943
OpenAlexW2394641649

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.