Evidence map›Paper›PMID 27189322›Full record

ArticleEuropean journal of cancer (Oxford, England : 1990)2016

RECIST 1.1-Update and clarification: From the RECIST committee.

Lawrence H Schwartz, Saskia Litière, Elisabeth de Vries, Robert Ford, Stephen Gwyther, Sumithra Mandrekar, Lalitha Shankar, Jan Bogaerts, Alice Chen, Janet Dancey and 9 more

4 registry-linked trialsAbstract read
In one paragraph

Article in European journal of cancer (Oxford, England : 1990), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 1,217 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,217citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03637868 phase2withdrawnnot on this mapstarted 2019, after this paper: background citation

A Phase II Study of Eribulin in Brain Metastases From HER2-negative Breast Cancer Pre-treated With Anthracyclines and Taxanes

TypeinterventionalSponsorInstitut Paoli-CalmettesRan2019 to 2020Enrolled0ConditionsMetastatic Breast CancerArmsEribulin
NCT05291780 nacompletednot on this map

STereotactic Ablative RadioTherapy in NEWly Diagnosed and Recurrent Locally Advanced Non-small Cell Lung Canter Patients Unfit for concurrEnt RAdio-chemotherapy

TypeinterventionalSponsorRadiotherapy Oncology Centre "Santa Maria" HospitalRan2015 to 2021Enrolled80ConditionsLocally Advanced Lung Non-Small Cell CarcinomaArmsStereotactic Ablative Radiotherapy in Unresectable Locally Advanced Non-Small Cell Lung Cancer
NCT06262386 narecruitingnot on this mapstarted 2023, after this paper: background citation

Utilizing Perioperative Variation Trends of Circulating Tumor Cells and Tumor Pathological Characteristics as a Combined Relapse Prediction Model for Resectable Non-Small Cell Patients - a Prospective Clinical Feasibility Trial

TypeinterventionalSponsorChang Gung Memorial HospitalRan2023 to 2028Enrolled358ConditionsLung Cancer, Relapse/RecurrenceArmsCisplatin based chemottherapy
NCT06582745 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

Targeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, Trametinib

TypeinterventionalSponsorCook Children's Health Care SystemRan2024 to 2039Enrolled75ConditionsLangerhans Cell HistiocytosisArmsTrametinib
3 · Its place in the literature

Who cites it

1,217 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. A Multicentre Phase II Study of Trifluridine/Tipiracil in Recurrent/Metastatic Platinum-Resistant Nasopharyngeal Carcinomas.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
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  15. Article
  16. Observational
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  19. Review
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1,157 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Lawrence H SchwartzDepartment of Radiology, Columbia University Medical Center, New York, NY, USA; New York Presbyterian Hospital, New York, NY, USA. Electronic address: LSchwartz@columbia.edu.
Saskia LitièreEORTC HQ, Brussels, Belgium.
Elisabeth de VriesDepartment of Internal Medicine, University Medical Center Groningen, Groningen, The Netherlands.
Robert FordClinical Trials Imaging Consulting, NJ, USA.
Stephen GwytherDepartment of Medical Imaging, East Surrey Hospital, Redhill, Surrey, UK.
Sumithra MandrekarDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.
Lalitha ShankarClinical Trials Branch, Cancer Imaging Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD, USA.
Jan BogaertsEORTC HQ, Brussels, Belgium.
Alice ChenEarly Clinical Trials Development Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD, USA.
Janet DanceyCanadian Cancer Trials Group, Queen's University, Kingston, Canada.
Wendy HayesExploratory Clinical & Translational Research, Bristol-Myers Squibb, Princeton, NJ, USA.
F Stephen HodiDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Otto S HoekstraDepartment of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands.
Erich P HuangNational Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Nancy LinDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Yan LiuEORTC HQ, Brussels, Belgium.
Patrick TherasseLaboratoires Servier, Paris, France.
Jedd D WolchokDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical and Graduate Colleges, New York, NY, USA; Ludwig Institute for Cancer Research, New York, NY, USA.
Lesley SeymourCanadian Cancer Trials Group, Queen's University, Kingston, Canada.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
EORTC HEADQUARTERSU10CA011488 · NCI · EUROPEAN ORG/RES/TREATMENT/CANCER · PI LACOMBE, DENIS · 1985 to 2015
$6.6M
NCI NIH HHS P30 CA008748NCI NIH HHS U10 CA011488
6 · The paper itself

Abstract

The Response Evaluation Criteria in Solid Tumours (RECIST) were developed and published in 2000, based on the original World Health Organisation guidelines first published in 1981. In 2009, revisions were made (RECIST 1.1) incorporating major changes, including a reduction in the number of lesions to be assessed, a new measurement method to classify lymph nodes as pathologic or normal, the clarification of the requirement to confirm a complete response or partial response and new methodologies for more appropriate measurement of disease progression. The purpose of this paper was to summarise the questions posed and the clarifications provided as an update to the 2009 publication.

Indexed as

Response Evaluation Criteria in Solid TumorsAdvisory CommitteesDisease ProgressionHumansLymph NodesNeoplasmsTomography, X-Ray ComputedTreatment OutcomeClarificationsRECISTTumour response

Identifiers

PMID27189322
PMCPMC5737828

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.