Evidence map›Paper›PMID 27189022›Full record

ArticleEuropean journal of human genetics : EJHG2016

A splice variant in the ACSL5 gene relates migraine with fatty acid activation in mitochondria.

Fuencisla Matesanz, María Fedetz, Cristina Barrionuevo, Mohamad Karaky, Antonio Catalá-Rabasa, Victor Potenciano, Raquel Bello-Morales, Jose-Antonio López-Guerrero, Antonio Alcina

Open access · hybridAbstract read
In one paragraph

Article in European journal of human genetics : EJHG, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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  9. The role of dihydrosphingolipids in disease.Cellular and molecular life sciences : CMLS · 2019
    Review
  10. Genetics of hearing loss in the Arab population of Northern Israel.European journal of human genetics : EJHG · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Fuencisla MatesanzDepartment of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina López Neyra (IPBLN), Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
María FedetzDepartment of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina López Neyra (IPBLN), Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Cristina BarrionuevoDepartment of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina López Neyra (IPBLN), Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Mohamad KarakyDepartment of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina López Neyra (IPBLN), Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Antonio Catalá-RabasaDepartment of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina López Neyra (IPBLN), Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Victor PotencianoDepartment of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina López Neyra (IPBLN), Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Raquel Bello-MoralesDepartamento de Biología Molecular, Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Jose-Antonio López-GuerreroDepartamento de Biología Molecular, Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Antonio AlcinaDepartment of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina López Neyra (IPBLN), Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Consejo Superior de Investigaciones Científicas · ESInstituto de Parasitología y Biomedicina "López - Neyra" · ESUniversidad Autónoma de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome-wide association studies (GWAS) in migraine are providing the molecular basis of this heterogeneous disease, but the understanding of its aetiology is still incomplete. Although some biomarkers have currently been accepted for migraine, large amount of studies for identifying new ones is needed. The migraine-associated variant rs12355831:A>G (P=2 × 10

Indexed as

RNA SplicingSequence DeletionCoenzyme A LigasesExonsFatty AcidsGenome-Wide Association StudyHEK293 CellsHumansLinkage DisequilibriumMigraine DisordersMitochondriaACSL5 protein, humanCoenzyme A LigasesFatty Acids

Identifiers

PMID27189022
PMCPMC5110053
OpenAlexW2404566918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.