ArticleBMJ open2016
Prevalence and trends of sensitisation to aeroallergens in patients with allergic rhinitis in Guangzhou, China: a 10-year retrospective study.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 51 citations in OpenAlex.
- Association of Cat Sensitization With Comorbid Asthma in Patients With Allergic Rhinitis: A Real-World Study.World journal of otorhinolaryngology - head and neck surgery · 2026Article
- Landscape of Aeroallergen Sensitization in Asia.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025Review
- Sensitization to inhaled and food allergen sources in patients with allergic diseases in Eastern China.Frontiers in allergy · 2025Article
- Aeroallergen Sensitization Patterns and Related Factors in Children With Allergic Rhinitis in Guangzhou.Mediators of inflammation · 2025Article
- Prevalence of allergic sensitization toAsia Pacific allergy · 2024Article
- Multicenter study of seasonal and regional airborne allergens in Chinese preschoolers with allergic rhinitis.Scientific reports · 2024Article
- Risk factors of allergic rhinitis and its prevention strategies.Frontiers in allergy · 2024Review
- Prevalence of allergen sensitization among children with allergic rhinitis in Changzhou, China: a retrospective observational study.BMC pediatrics · 2023Observational
- Fungal Aeroallergen Sensitization Patterns among Airway-Allergic Patients in Zagazig, Egypt.Journal of fungi (Basel, Switzerland) · 2023Article
- Chinese Guideline on Allergen Immunotherapy for Allergic Rhinitis: The 2022 Update.Allergy, asthma & immunology research · 2022Review
- Epithelial barrier hypothesis: Effect of the external exposome on the microbiome and epithelial barriers in allergic disease.Allergy · 2022Review
- Environmental and sensitization variations among asthma and/or rhinitis patients between 2008 and 2018 in China.Clinical and translational allergy · 2022Article
- Chinese Central Compartment Atopic Disease: The Clinical Characteristics and Cellular Endotypes Based on Whole-Slide Imaging.Journal of asthma and allergy · 2022Article
- Prevalence of Sensitization to Aeroallergens in Greater Beijing Region Children With Respiratory Allergy.Frontiers in pediatrics · 2022Article
- Sensitization to Furry Animals in Patients with Suspected Allergic Disease in China: A Multicenter Study.Journal of asthma and allergy · 2022Article
- Developing nomograms for identifying allergic rhinitis among chronic rhinitis: A real-world study.The World Allergy Organization journal · 2021Article
- [Sensitization pattern of cat and dog dander allergen in 16 426 patients with allergic diseases].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021Article
- China Consensus Document on Allergy Diagnostics.Allergy, asthma & immunology research · 2021Review
- Using the Internet Big Data to Investigate the Epidemiological Characteristics of Allergic Rhinitis and Allergic Conjunctivitis.Risk management and healthcare policy · 2021Article
- Prevalence of Aeroallergens in Allergic Rhinitis in a Tertiary Care Hospital.JNMA; journal of the Nepal Medical Association · 2020Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the prevalence and trends of sensitisation to common aeroallergens among outpatients with allergic rhinitis (AR) in Guangzhou, China, over the past decade.
designA retrospective study; linear-by-linear association and simple linear regression were used to determine the trends in the prevalence of aeroallergen sensitisation.
settingOne grade-A hospital in Guangzhou, the largest city in southern China.
participantsA total of 5486 patients (2297 males and 2489 females) who visited the ear, nose and throat outpatient clinic, from January 2005 to December 2014, were enrolled. All patients who presented with nasal hyper-reactive symptoms and who completed serological allergy testing, measuring specific IgE (sIgE) in the serum, were included. Among them, 4085 participants (2269 males and 1816 females) were diagnosed as being patients with AR. OUTCOME MEASURES: Prevalence and trends of sensitisation to various types of aeroallergens were assessed.
resultsThe overall prevalence of sIgE-mediated sensitisation to aeroallergens in these patients with AR were as follows: 84.4% for house dust mites (HDMs), 23.4% for pet allergens, 21.1% for cockroaches, 9.1% for mould allergens, 7.7% for tree pollen and 6.0% for weed pollen. When all patients with nasal hyper-reactivity were stratified by decade of age, increasing age was associated with a decrease in sIgE positivity by ∼5.13% (95% CI -7.28% to -2.98%, p<0.01). Within the past decade, the prevalence of sensitisation to pet allergens in patients with AR increased at an annual rate of 1.3% (95% CI 0.85% to 1.67%, p<0.01).
conclusionsThis study demonstrated that HDMs comprised the most common aeroallergen in Guangzhou. The prevalence of sensitisation to aeroallergens decreased with increasing age. During the past decade, the prevalence of sensitisation to pet allergens showed an upward trend, suggesting an urgent need for its prevention and treatment.
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