ArticleNature communications2016
Alanine aminotransferase controls seed dormancy in barley.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
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Who cites it
81 citing papers in PubMed, 163 citations in OpenAlex.
- Genomic and evolutionary analysis reveals dynamic variations of MKK3 gene, a key regulator for seed dormancy in barley.The plant genome · 2026Article
- The SD1 locus affects primary seed dormancy in winter malting barley.The plant genome · 2026Article
- Identification of adaptive selection footprints and adaptation strategies of hulless barley (Hordeum vulgare var. coeleste) on the Qinghai-Tibet Plateau.BMC genomics · 2026Article
- Going against the grain: Investigating C4 photosynthesis in the wheat grain with spatial transcriptomics.BMC plant biology · 2026Article
- Successful Modification of a Commercial Wheat Variety, Lunxuan 13, for Pre-Harvest Sprouting Resistance Through Editing of thePlants (Basel, Switzerland) · 2026Article
- Detection of bsd1, a gene responsible for breaking seed dormancy by machine threshing in barley (Hordeum vulgare L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Dormancy Versus Germination: 3D Protein Modeling and Evolutionary Analyses Define the Roles of Genetic Variants in the Barley MKK3 Enzyme.International journal of molecular sciences · 2026Article
- Translating research on seed dormancy and germination from Arabidopsis to temperate cereals to control pre-harvest sprouting.Frontiers in plant science · 2026Review
- Impact of wheat GRF4-GIF1 morphogenic regulators on transformation and genome editing efficiency in elite barley cultivars.Frontiers in plant science · 2026Article
- Genetic improvement of resistance to preharvest sprouting using a major QTL allele for embryo dormancy in rice.Molecular breeding : new strategies in plant improvement · 2025Article
- JA-Mediated Regulation of Amino Acid Homeostasis Adjusts Metabolic Flux and Enhances Spider Mite Tolerance via the SlJAZ8-SlWRKY57-SlAVT6s Module in Tomato.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Breeding of Fukumi Fiber, a new six-rowed waxy hull-less barley cultivar containing high levels of β-glucan with a proanthocyanidin-free gene.Breeding science · 2025Article
- Alanine aminotransferase contributes to hypoxia sensitivity and dormancy in barley seeds.The plant genome · 2025Article
- Introgression of dwarfing allele dw1 reduced seed dormancy and increased pre-harvest sprouting susceptibility in grain sorghum converted lines.Plant biotechnology journal · 2025Article
- Identification of QTLs associated with grain yield-related traits of spring barley.BMC plant biology · 2025Article
- Development of a KASP marker set for high-throughput genotyping in Japanese barley breeding programs with various end-use purposes.Breeding science · 2025Article
- Genetic resources and pangenome analysis of barley.Breeding science · 2025Article
- Multi-locus genome wide association study uncovers genetics of fresh seed dormancy in groundnut.BMC plant biology · 2024Article
- Advances in seed hypoxia research.Plant physiology · 2024Article
- Role of alanine aminotransferase in crop resilience to climate change: a critical review.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
21 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dormancy allows wild barley grains to survive dry summers in the Near East. After domestication, barley was selected for shorter dormancy periods. Here we isolate the major seed dormancy gene qsd1 from wild barley, which encodes an alanine aminotransferase (AlaAT). The seed dormancy gene is expressed specifically in the embryo. The AlaAT isoenzymes encoded by the long and short dormancy alleles differ in a single amino acid residue. The reduced dormancy allele Qsd1 evolved from barleys that were first domesticated in the southern Levant and had the long dormancy qsd1 allele that can be traced back to wild barleys. The reduced dormancy mutation likely contributed to the enhanced performance of barley in industrial applications such as beer and whisky production, which involve controlled germination. In contrast, the long dormancy allele might be used to control pre-harvest sprouting in higher rainfall areas to enhance global adaptation of barley.
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