ArticleThe ISME journal2016
Biogeography of sulfur-oxidizing Acidithiobacillus populations in extremely acidic cave biofilms.
Article in The ISME journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Microbial succession and assembly shaped by sulfur, spatial partitioning, and water flow in a volcanic acidic river of northern Patagonia.The ISME journal · 2026Article
- Spatial and functional differentiation of microbial biofilms in a traditional cheese ripening environment.Scientific reports · 2025Article
- Article
- The geomicrobiology of limestone, sulfuric acid speleogenetic, and volcanic caves: basic concepts and future perspectives.Frontiers in microbiology · 2024Review
- Review
- Convergent Community Assembly among Globally Separated Acidic Cave Biofilms.Applied and environmental microbiology · 2023Article
- Habitat Adaptation Drives Speciation of amBio · 2022Article
- Culture-Independent Survey of Thermophilic Microbial Communities of the North Caucasus.Biology · 2021Article
- Genomic evolution of the class Acidithiobacillia: deep-branching Proteobacteria living in extreme acidic conditions.The ISME journal · 2021Article
- Genomic adaptations enabling Acidithiobacillus distribution across wide-ranging hot spring temperatures and pHs.Microbiome · 2021Article
- Draft Genome Sequences of Three Strains ofMicrobiology resource announcements · 2021Article
- Meta-Analysis of Microbial Communities in Hot Springs: Recurrent Taxa and Complex Shaping Factors beyond pH and Temperature.Microorganisms · 2020Article
- A Deeper Look into the Biodiversity of the Extremely Acidic Copahue volcano-Río Agrio System in Neuquén, Argentina.Microorganisms · 2019Article
- Paleo-Rock-Hosted Life on Earth and the Search on Mars: A Review and Strategy for Exploration.Astrobiology · 2019Review
- Historical Factors Associated With Past Environments Influence the Biogeography of Thermophilic Endospores in Arctic Marine Sediments.Frontiers in microbiology · 2019Article
- Article
- Molecular Systematics of the GenusFrontiers in microbiology · 2017Article
- Bioinformatic Analyses of Unique (Orphan) Core Genes of the GenusFrontiers in microbiology · 2016Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extremely acidic (pH 0-1.5) Acidithiobacillus-dominated biofilms known as snottites are found in sulfide-rich caves around the world. Given the extreme geochemistry and subsurface location of the biofilms, we hypothesized that snottite Acidithiobacillus populations would be genetically isolated. We therefore investigated biogeographic relationships among snottite Acidithiobacillus spp. separated by geographic distances ranging from meters to 1000s of kilometers. We determined genetic relationships among the populations using techniques with three levels of resolution: (i) 16S rRNA gene sequencing, (ii) 16S-23S intergenic transcribed spacer (ITS) region sequencing and (iii) multi-locus sequencing typing (MLST). We also used metagenomics to compare functional gene characteristics of select populations. Based on 16S rRNA genes, snottites in Italy and Mexico are dominated by different sulfur-oxidizing Acidithiobacillus spp. Based on ITS sequences, Acidithiobacillus thiooxidans strains from different cave systems in Italy are genetically distinct. Based on MLST of isolates from Italy, genetic distance is positively correlated with geographic distance both among and within caves. However, metagenomics revealed that At. thiooxidans populations from different cave systems in Italy have different sulfur oxidation pathways and potentially other significant differences in metabolic capabilities. In light of those genomic differences, we argue that the observed correlation between genetic and geographic distance among snottite Acidithiobacillus populations is partially explained by an evolutionary model in which separate cave systems were stochastically colonized by different ancestral surface populations, which then continued to diverge and adapt in situ.
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