ArticleBiosensors2016
A Flow SPR Immunosensor Based on a Sandwich Direct Method.
Article in Biosensors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Article
- Real-Time Monitoring of Antibiotics in the Critically Ill Using Biosensors.Antibiotics (Basel, Switzerland) · 2023Review
- Review
- Surface Plasmon Resonance for Protease Detection by Integration of Homogeneous Reaction.Biosensors · 2021Article
- Aptamer-Based Detection of Ampicillin in Urine Samples.Antibiotics (Basel, Switzerland) · 2020Article
- Optical Biosensors for Therapeutic Drug Monitoring.Biosensors · 2019Review
- Gold Nanoparticles Used as Protein Scavengers Enhance Surface Plasmon Resonance Signal.Sensors (Basel, Switzerland) · 2017Article
- Magnetic Nanoparticles for Antibiotics Detection.Nanomaterials (Basel, Switzerland) · 2017Review
- Comparison between a Direct-Flow SPR Immunosensor for Ampicillin and a Competitive Conventional Amperometric Device: Analytical Features and Possible Applications to Real Samples.Sensors (Basel, Switzerland) · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, we report the development of an SPR (Surface Plasmon Resonance) immunosensor for the detection of ampicillin, operating under flow conditions. SPR sensors based on both direct (with the immobilization of the antibody) and competitive (with the immobilization of the antigen) methods did not allow the detection of ampicillin. Therefore, a sandwich-based sensor was developed which showed a good linear response towards ampicillin between 10(-3) and 10(-1) M, a measurement time of ≤20 min and a high selectivity both towards β-lactam antibiotics and antibiotics of different classes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.