Evidence map›Paper›PMID 27187456›Full record

ArticleNutrients2016

High Prevalence of Vitamin D Deficiency in Cambodian Women: A Common Deficiency in a Sunny Country.

Geoffry Smith, Sunil J Wimalawansa, Arnaud Laillou, Prak Sophonneary, Samoeurn Un, Rathavuth Hong, Etienne Poirot, Khov Kuong, Chhoun Chamnan, Francisco N De Los Reyes and 1 more

Abstract read
In one paragraph

Article in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Vitamin D Levels and Prevalence of Vitamin D Deficiency in Turkish Women According to Regions and Age Groups.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  5. Article
  6. Article
  7. The Role of Micronutrients and Toxic Metals in the Management of Epidemics in Cambodia.International journal of environmental research and public health · 2021
    Review
  8. Article
  9. Article
  10. Observational
  11. Osteoporosis in South-East Asian Countries.The Clinical biochemist. Reviews · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Geoffry SmithInternational Life Sciences Institute, South East Asia Region, 9 Mohamed Sultan Road #02-01, Singapore 238959, Singapore. geoffsmith@ilsisea.org.sg.
Sunil J WimalawansaCardio Metabolic Institute, Medicine, Endocrinology & Nutrition, 661 Darmody Avenue, North Brunswick, NJ 08902, USA. suniljw@hotmail.com.
Arnaud LaillouUnited Nations Children's Fund (UNICEF), Maternal, Newborn and Child Health and Nutrition Section, No. 11 street 75, Phnom Penh 12202, Cambodia. alaillou@unicef.org.
Prak SophonnearyNational Nutrition Program, Maternal and Child Health Center, No. 31A, Rue de France (St. 47), Phnom Penh 12202, Cambodia. sophonprak@gmail.com.
Samoeurn UnUnited Nations Children's Fund (UNICEF), Maternal, Newborn and Child Health and Nutrition Section, No. 11 street 75, Phnom Penh 12202, Cambodia. sun@unicef.org.
Rathavuth HongICF International, 530 Gaither Road, Suite 500, Rockville, MD 20850, USA. rathavuth.hong@icfi.com.
Etienne PoirotUnited Nations Children's Fund (UNICEF), Maternal, Newborn and Child Health and Nutrition Section, No. 11 street 75, Phnom Penh 12202, Cambodia. epoirot@unicef.org.
Khov KuongDepartment of Fisheries Post-harvest Technologies and Quality control (DFPTQ), Fisheries Administration, Ministry of Agriculture, Forestry and Fisheries (MAFF), 186 Preah Norodom Boulevard, Phnom Penh 12000, Cambodia. kuong.kh@gmail.com.
Chhoun ChamnanDepartment of Fisheries Post-harvest Technologies and Quality control (DFPTQ), Fisheries Administration, Ministry of Agriculture, Forestry and Fisheries (MAFF), 186 Preah Norodom Boulevard, Phnom Penh 12000, Cambodia. chhounchamnan@gmail.com.
Francisco N De Los ReyesUniversity of the Philippines, Diliman, Quezon City 1101, Philippines. fndelosreyes@up.edu.ph.
Frank T WieringaInstitute of Research for Development (IRD), UMR Nutripass IRD-UM2-UM1, Montpellier 3400, France. franck.wieringa@ird.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have shown that in spite of being generally close to the equator; vitamin D deficiency is common in South East Asian countries. In order to quantify micronutrient status for women and children in Cambodia; a nationally-representative survey was conducted in 2014 linked to the Cambodian Demographic Health Survey. The countrywide median of 25(OH)D was, respectively, 64.9 and 91.1 nmol/L for mothers and children. Based on The Endocrine Society cutoffs (>50<75 nmol/L = insufficiency; ≤50 nmol/L = deficiency); 64.6% of mothers and 34.8% of their children had plasma vitamin D concentrations indicating insufficiency or deficiency. For deficiency alone, 29% of the mothers were found to be vitamin D deficient, but only 13.4% of children. Children who live in urban areas had a 43% higher rate of vitamin D insufficiency versus those who live in rural areas (OR; 1.434; 95% CI: 1.007; 2.041). However, such differences were not observed in their mothers. The high prevalence of vitamin D deficiency is likely in part due to lifestyle choices, including sun avoidance, increasingly predominant indoor work, and covered transport. These survey findings support the need for a broader national Cambodian study incorporating testing of adult men, adolescents and the elderly, and encompassing other parameters such as skeletal health. However, the data presented in this study already show significant deficiencies which need to be addressed and we discuss the benefit of establishing nationally-mandated food fortification programs to enhance the intake of vitamin D.

Indexed as

SunlightAdolescentAdultCambodiaDemographyFemaleHumansMiddle AgedPrevalenceRisk FactorsSocioeconomic FactorsVitamin DVitamin D Deficiency25-hydroxyvitamin DVitamin DCambodiaDemographic Health Survey Nutritionnational surveySouth East Asiavitamin D

Identifiers

PMID27187456
PMCPMC4882703

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.