ArticlePLoS neglected tropical diseases2016
Cholera Incidence and Mortality in Sub-Saharan African Sites during Multi-country Surveillance.
Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Estimating the proportion of clinically suspected cholera cases that are true Vibrio cholerae infections: A systematic review and meta-analysis.PLoS medicine · 2023Pooled it
- Prevalence and diversity of enteric pathogens among cholera treatment centre patients with acute diarrhea in Uvira, Democratic Republic of Congo.BMC infectious diseases · 2020Trial
- Two decades of cholera in Dhaka, Bangladesh: Epidemiology, seasonal patterns, and environmental risk, insights from 2004-2024.PLoS neglected tropical diseases · 2026Article
- Water, Hygiene and Inequality: Keys to Understanding and Combating the Current Cholera Epidemic in the Democratic Republic of Congo-A Narrative Review.Health science reports · 2026Article
- Cholera surveillance time series in Africa between 2010 and 2023.Gates open research · 2026Article
- Unmasking and tackling the underestimation of the cholera burden in Africa: A viewpoint.PLoS neglected tropical diseases · 2025Review
- Navigating the cholera elimination roadmap in Zambia - A scoping review (2013-2024).PLoS neglected tropical diseases · 2025Article
- Navigating water crisis, cholera, and refugee context: Lessons from Nakivale refugee settlement, Isingiro District, Uganda.PLOS global public health · 2025Article
- Enhanced cholera surveillance to improve vaccination campaign efficiency.Nature medicine · 2024Article
- Rapid cholera outbreak control following catastrophic landslides and floods: A case study of Bududa district, Uganda.African health sciences · 2023Article
- Inadequate Hand Washing, Lack of Clean Drinking Water and Latrines as Major Determinants of Cholera Outbreak in Somali Region, Ethiopia in 2019.Frontiers in public health · 2022Article
- Contrasting Epidemiology of Cholera in Bangladesh and Africa.The Journal of infectious diseases · 2021Review
- Clinical, Sociodemographic and Environmental Risk Factors for Acute Bacterial Diarrhea among Adults and Children over Five Years in Bangladesh.The American journal of tropical medicine and hygiene · 2021Article
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- Cholera risk in cities in Uganda: understanding cases and contacts centered strategy (3CS) for rapid cholera outbreak control.The Pan African medical journal · 2021Article
- Post-infection irritable bowel syndrome in the tropical and subtropical regions: Vibrio cholerae is a new cause of this well-known condition.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019Review
- Review
- Sensitivity, Specificity, and Public-Health Utility of Clinical Case Definitions Based on the Signs and Symptoms of Cholera in Africa.The American journal of tropical medicine and hygiene · 2018Article
- Article
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33 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCholera burden in Africa remains unknown, often because of weak national surveillance systems. We analyzed data from the African Cholera Surveillance Network (www.africhol.org). METHODS/ PRINCIPAL
findingsDuring June 2011-December 2013, we conducted enhanced surveillance in seven zones and four outbreak sites in Togo, the Democratic Republic of Congo (DRC), Guinea, Uganda, Mozambique and Cote d'Ivoire. All health facilities treating cholera cases were included. Cholera incidences were calculated using culture-confirmed cholera cases and culture-confirmed cholera cases corrected for lack of culture testing usually due to overwhelmed health systems and imperfect test sensitivity. Of 13,377 reported suspected cases, 34% occurred in Conakry, Guinea, 47% in Goma, DRC, and 19% in the remaining sites. From 0-40% of suspected cases were aged under five years and from 0.3-86% had rice water stools. Within surveillance zones, 0-37% of suspected cases had confirmed cholera compared to 27-38% during outbreaks. Annual confirmed incidence per 10,000 population was <0.5 in surveillance zones, except Goma where it was 4.6. Goma and Conakry had corrected incidences of 20.2 and 5.8 respectively, while the other zones a median of 0.3. During outbreaks, corrected incidence varied from 2.6 to 13.0. Case fatality ratios ranged from 0-10% (median, 1%) by country. CONCLUSIONS/SIGNIFICANCE: Across different African epidemiological contexts, substantial variation occurred in cholera incidence, age distribution, clinical presentation, culture confirmation, and testing frequency. These results can help guide preventive activities, including vaccine use.
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