ArticleSpringerPlus2016
Tuberculosis in infants: a retrospective study in China.
Article in SpringerPlus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interferon-γ release assay and mantoux response in infants with tuberculous meningitis in low and intermediate burden countries.BMC infectious diseases · 2023Pooled it
- Cerebrospinal fluid findings of infant tuberculous meningitis: a scoping review.Annals of medicine · 2022Article
- Tuberculous meningitis during infancy: 26 cases in South Turkey among 20 years.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Heterogenous Immune Response to TB is Not a False Negative.The American journal of tropical medicine and hygiene · 2020Article
- Epidemiological Trends in the Form of Childhood Tuberculosis in a Referral Tuberculosis Hospital in Shandong, China.BioMed research international · 2020Article
- The burden and challenges of tuberculosis in China: findings from the Global Burden of Disease Study 2015.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
To describe the demographics, clinical characteristics and microbiologic findings of infant (≤2 years old) tuberculosis (TB) in a high TB burden country. Between Feb, 2007 and Jun, 2015, 115 TB infants who admitted to our hospital were enrolled in the study. Their clinicopathological characteristics were reviewed and analyzed. The mean age was 10.1 ± 7.4 (SD) months, and 84 of 115 infants (73.0 %) were males. 23 patients (20.0 %) had isolated pulmonary TB, 18 patients (15.7 %) had pulmonary and extrapulmonary TB (EPTB), the remaining 74 patients (64.4 %) had exclusively EPTB. The most common site of EPTB was lymph node (n = 61), 54 cases were left axillary lymph node involvement. 49 of 51 patients (96.1 %) were validated by pathological examination, 5 of 57 patients (8.8 %) were positive on acid fast bacilli smear, and 27 of 103 patients (26.2 %) were confirmed by mycobacterial culture. 29 of 59 patients (49.2 %) were PPD positive, 14 of 30 patients (46.7 %) were T-SPOT.TB positive. The most common complaints of patients were lymph node swelling (53.0 %), fever (36.5 %), cough (28.7 %) and dyspnea (10.4 %). There was significant difference in the time before hospital admission among different types of tuberculosis (P < 0.01), fever was also a factor influencing the time (P < 0.05). In infants, the sensitivities of routine TB tests were low and emphasize the need for improved diagnostics; EPTB was more common than pulmonary TB, tuberculous lymphadenitis constituted a high proportion of EPTB; there appears to be an association between the incidence of axillary lymph node TB and BCG vaccination among infants in China.
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