ReviewIranian Red Crescent medical journal2016
The Most Common Herbs to Cure the Most Common Oral Disease: Stomatitis Recurrent Aphthous Ulcer (RAU).
Review in Iranian Red Crescent medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Systematic review and meta-analysis of oxidative stress and antioxidant markers in recurrent aphthous stomatitis.BMC oral health · 2023Pooled it
- Association of IL-6-174 G/C and IL10-1082 G/A polymorphisms with recurrent aphthous stomatitis risk: A meta-analysis.Medicine · 2017Pooled it
- Comparison of Two Oral Pastes Containing Triamcinolone and Rhus Coriaria L. for Treating Minor Aphthous Lesions.International dental journal · 2025Trial
- Evaluation of the Effects of Punica granatum Flower Tablets on Pain and Healing of Minor Recurrent Aphthous Stomatitis: A Randomized Clinical Trial.Clinical and experimental dental research · 2024Trial
- OTUD6A-Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Dietary Antioxidant Index and the Risk of Recurrent Aphthous Stomatitis.International dental journal · 2025Article
- The healing effect of nano emulsified Plantago major L extract on oral wounds in a wistar rat model.BMC complementary medicine and therapies · 2024Article
- Optimization and preparation of a compound cod liver oil film former agent: an orthogonal design.Frontiers in pharmacology · 2024Article
- Article
- Efficacy of Oral Mucoadhesive N-Acetylcysteine Tablets in Treatment of Recurrent Aphthous Stomatitis: A Randomized Double-Blind, Placebo-Controlled Clinical Trial.Frontiers in dentistry · 2023Article
- Wound Healing and Anti-Inflammatory Effects of a Newly Developed Ointment Containing Jujube Leaves Extract.Life (Basel, Switzerland) · 2022Article
- Can Plant Materials Be Valuable in the Treatment of Periodontal Diseases? Practical Review.Pharmaceutics · 2021Review
- Use of traditional medicine for dental care by different ethnic groups in New Zealand.BMC oral health · 2020Article
- Effect of Shuangjinlian mixture on oral ulcer model in rat.Saudi journal of biological sciences · 2019Article
- Recurrent aphthous ulceration: an epidemiological study of etiological factors, treatment and differential diagnosis.Anais brasileiros de dermatologia · 2018Article
- Plantago major in Traditional Persian Medicine and modern phytotherapy: a narrative review.Electronic physician · 2018Review
- Analysis of Dietary Related Factors of Recurrent Aphthous Stomatitis among College Students.Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Systemic bioinformatics analysis of recurrent aphthous stomatitis gene expression profiles.Oncotarget · 2017Article
- Atypical Afta Major Healing after Photodynamic Therapy.Case reports in dentistry · 2017Article
- The Effect of Pudilan Anti-Inflammatory Oral Liquid on the Treatment of Mild Recurrent Aphthous Ulcers.Evidence-based complementary and alternative medicine : eCAM · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextRecurrent aphthous ulcer (RAU) is an oral disease and the most common oral lesion, with 2% to 66% of the world's population infected annually. Its prevalence is about 25% in Tehran and 27.6% in Mashhad. The etiology of RAU is multifactorial. Aphthous risk factors include: immunological factors, psychological factors, stress, trauma, sensitivity, family history, blood disorders, malnutrition, and use of certain medications, It should be noted that the best treatment for RAU is the topical application of drugs. The use of topical treatments is recommended not only because the drug can directly impact the source of the disease, but also systemic side effects of the drug are reduced. Treatment of RAU has been considered in Iranian traditional medicine (ITM), and is covered in therapeutic books. The use of herbs in RAU has a centuries-old history; accordingly, extensive research should be conducted for this treatment of the disease. EVIDENCE ACQUISITION: Iranian medical sources were reviewed and effective plants used in the traditional treatment of RAU were found and compared with new findings. Finally, we have created a table listing the plants that are part of the therapeutic protocol for RAU.
resultsBased on this article we can explain some of traditional pharmacological effects of plants and how these plants can be a source for a cure.
conclusionsThe plants listed can be used as a prediction of RAU management. Of course, there are is no evidence for curing RAU by some of these plants in allopathic medicine, and the further investigations in this area could lead to the discovery of a new drug.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.