Evidence map›Paper›PMID 27185603›Full record

ArticleThe Kaohsiung journal of medical sciences2016

Ischemia-modified albumin levels in the prediction of acute critical neurological findings in carbon monoxide poisoning.

Murat Daş, Yunsur Çevik, Özcan Erel, Şeref Kerem Çorbacioğlu

Open access · goldAbstract read
In one paragraph

Article in The Kaohsiung journal of medical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Murat DaşDepartment of Emergency Medicine, Edremit State Hospital, Balıkesir, Turkey.
Yunsur ÇevikDepartment of Emergency Medicine, Kecioren Training and Research Hospital, Ankara, Turkey.
Özcan ErelDepartment of Biochemistry, Yıldırım Beyazıt University Faculty of Medicine, Ankara, Turkey.
Şeref Kerem ÇorbacioğluDepartment of Emergency Medicine, Kecioren Training and Research Hospital, Ankara, Turkey. Electronic address: serefkeremcorbacioglu@gmail.com.
Ankara Yıldırım Beyazıt University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to determine whether serum ischemia-modified albumin (IMA) levels in patients with carbon monoxide (CO) poisoning were higher compared with a control group of healthy volunteers. In addition, the study sought to determine if there was a correlation between serum IMA levels and carboxyhemoglobin (COHB) levels and other critical neurological findings (CNFs). In this prospective study, the IMA levels of 100 patients with CO poisoning and 50 control individuals were compared. In addition, the IMA and COHB levels were analyzed according to absence or presence CNFs in patients with CO poisoning. The levels of IMA (mg/dL) on admittance, and during the 1(st) hour and 3(rd) hour, in patients with CO poisoning (49.90 ± 35.43, 30.21 ± 14.81, and 21.87 ± 6.03) were significantly higher, compared with the control individuals (17.30 ± 2.88). The levels of IMA in the 6(th) hour were not higher compared with control individuals. The levels of IMA on admittance, and during the 1(st) hour, 3(rd) hour, and 6(th) hour, and COHB (%) levels in patients who had CNFs were higher compared with IMA levels and COHB levels in patients who had no CNFs (p < 0.001). However, when the multivariate model was created, it was observed that IMA level on admittance was a poor indicator for prediction of CNFs (odds ratio = 1.05; 95% confidence interval, 1.01-1.08). We therefore concluded that serum IMA levels could be helpful in the diagnosis of CO poisoning. However, we believe that IMA levels cannot be used to predict which patients will develop CNFs due to CO poisoning.

Indexed as

AdultBiomarkersCarbon Monoxide PoisoningDemographyFemaleGlasgow Coma ScaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisSerum AlbuminSerum Albumin, HumanTime FactorsYoung AdultBiomarkersischemia-modified albuminSerum AlbuminSerum Albumin, HumanBiomarkers/exposure assessmentCarbon monoxideCarboxyhemoglobinIschemia-modified albuminNeurotoxicology

Identifiers

PMID27185603
PMCPMC11916829
OpenAlexW2343827983

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.