ArticleScientific reports2016
Regulation of Irregular Neuronal Firing by Autaptic Transmission.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- The mesencephalic trigeminal neuron: electrophysiological insights into function and dysfunction.Frontiers in cellular neuroscience · 2026Review
- Article
- Influence of inhibitory autapses on synchronization of inhibitory network gamma oscillations.Cognitive neurodynamics · 2023Article
- Hippocampal and Medial Prefrontal Cortex Fractal Spiking Patterns Encode Episodes and Rules.Chaos, solitons, and fractals · 2023Article
- Effect of steady-state response versus excitatory/inhibitory balance on spiking synchronization in neural networks with log-normal synaptic weight distribution.Cognitive neurodynamics · 2022Article
- Control of noise-induced coherent oscillations in three-neuron motifs.Cognitive neurodynamics · 2022Article
- Effects of synaptic integration on the dynamics and computational performance of spiking neural network.Cognitive neurodynamics · 2020Article
- Different dynamical behaviors induced by slow excitatory feedback for type II and III excitabilities.Scientific reports · 2020Article
- Article
- Autaptic Cultures: Methods and Applications.Frontiers in synaptic neuroscience · 2020Article
- Influence of Autapses on Synchronization in Neural Networks With Chemical Synapses.Frontiers in systems neuroscience · 2020Article
- A cortical model with multi-layers to study visual attentional modulation of neurons at the synaptic level.Cognitive neurodynamics · 2019Article
- Bistable Firing Pattern in a Neural Network Model.Frontiers in computational neuroscience · 2019Article
- Effect of external periodic signals and electromagnetic radiation on autaptic regulation of neuronal firing.IET systems biology · 2018Article
- Analytically determining frequency and amplitude of spontaneous alpha oscillation in Jansen's neural mass model using the describing function method.Chinese physics B = Zhongguo wu li B · 2018Article
- Effects of channel blocking on information transmission and energy efficiency in squid giant axons.Journal of computational neuroscience · 2018Article
- Measuring spike timing distance in the Hindmarsh-Rose neurons.Cognitive neurodynamics · 2018Article
- Controlling mechanism of absence seizures by deep brain stimulus applied on subthalamic nucleus.Cognitive neurodynamics · 2018Article
- Constraints of Metabolic Energy on the Number of Synaptic Connections of Neurons and the Density of Neuronal Networks.Frontiers in computational neuroscience · 2018Article
- Stimulus-induced transitions between spike-wave discharges and spindles with the modulation of thalamic reticular nucleus.Journal of computational neuroscience · 2017Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The importance of self-feedback autaptic transmission in modulating spike-time irregularity is still poorly understood. By using a biophysical model that incorporates autaptic coupling, we here show that self-innervation of neurons participates in the modulation of irregular neuronal firing, primarily by regulating the occurrence frequency of burst firing. In particular, we find that both excitatory and electrical autapses increase the occurrence of burst firing, thus reducing neuronal firing regularity. In contrast, inhibitory autapses suppress burst firing and therefore tend to improve the regularity of neuronal firing. Importantly, we show that these findings are independent of the firing properties of individual neurons, and as such can be observed for neurons operating in different modes. Our results provide an insightful mechanistic understanding of how different types of autapses shape irregular firing at the single-neuron level, and they highlight the functional importance of autaptic self-innervation in taming and modulating neurodynamics.
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