ArticleUltrasonography (Seoul, Korea)2016
Malignant-looking thyroid nodules with size reduction: core needle biopsy results.
Article in Ultrasonography (Seoul, Korea), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of ultrasound-guided fine needle aspiration cytology for diagnosis of thyroid nodules.Medicine · 2019Pooled it
- Long-Term Ultrasound Surveillance of Solid and Predominantly Solid Thyroid Nodules Reveals Two Distinct Absorption Patterns.Radiology research and practice · 2026Article
- Long-term follow-up of the radiofrequency ablation of benign thyroid nodules: the value of additional treatment.Ultrasonography (Seoul, Korea) · 2022Article
- Contrast-enhanced ultrasound improves the potency of fine-needle aspiration in thyroid nodules with high inadequate risk.BMC medical imaging · 2022Article
- Effect of the size of benign thyroid degenerative nodules on ACR TI-RADS categories.Journal of medical ultrasonics (2001) · 2022Article
- Ultrasound malignancy risk stratification of thyroid nodules based on the degree of hypoechogenicity and echotexture.European radiology · 2020Article
- Ultrasound-Guided Core Needle Biopsy Techniques for Intermediate or Low Suspicion Thyroid Nodules: Which Method is Effective for Diagnosis?Korean journal of radiology · 2019Article
- Degenerating Thyroid Nodules: Ultrasound Diagnosis, Clinical Significance, and Management.Korean journal of radiology · 2019Review
- Reliability of core needle biopsy as a second-line procedure in thyroid nodules with an indeterminate fine-needle aspiration report: a systematic review and meta-analysis.Ultrasonography (Seoul, Korea) · 2018Article
- Current status of core needle biopsy of the thyroid.Ultrasonography (Seoul, Korea) · 2017Article
- Ultrasonographic Interval Changes in Solid Thyroid Nodules after Ultrasonography-Guided Fine-Needle Aspiration.Korean journal of radiologyArticle
- Ultrasonographic Echogenicity and Histopathologic Correlation of Thyroid Nodules in Core Needle Biopsy Specimens.Korean journal of radiologyArticle
- Diagnostic Accuracy of Ultrasonography in Classifying Thyroid Nodules Compared with Fine-Needle Aspiration.Saudi journal of medicine & medical sciencesArticle
- Core Needle Biopsy of the Thyroid: 2016 Consensus Statement and Recommendations from Korean Society of Thyroid Radiology.Korean journal of radiologyReview
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to evaluate whether malignant-looking thyroid nodules with size reduction were malignant or not.
methodsFrom November 2010 to July 2011, we retrospectively enrolled 16 patients with 16 nodules (11 females and five males; mean age, 55 years) who underwent core needle biopsy (CNB), and whose thyroid nodules had malignant ultrasonographic (US) features, although they showed size reduction (>20% decrease in maximum diameter) during the follow-up period (mean, 37±27 months). The histologic findings of the CNB specimen were reviewed and correlated with the US findings. US studies were analyzed for their internal content, shape, margin, echogenicity, the presence of microcalcification and macrocalcification, inner isoechoic rim, and low-echoic halo.
resultsAll nodules were confirmed as benign by CNB. Pathologic analysis was available for 12 CNB specimens. US imaging showed central hypoechogenicity or marked hypoechogenicity in all cases and a peripheral isoechoic rim in 15 nodules. US-pathologic correlation showed that the central hypoechoic area was primarily composed of fibrosis (12/12) and hemorrhage (8/12) and that the isoechoic rim was composed of follicular cells.
conclusionIn our study, the CNB results of all of the malignant-looking thyroid nodules with size reduction were benign and were primarily composed of internal fibrosis and hemorrhage. Understanding these US and pathologic features could prevent repeated fine-needle aspiration or unnecessary diagnostic surgery.
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