Evidence map›Paper›PMID 27184637›Full record

ArticleSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

Efficacy of contrast-enhanced harmonic endoscopic ultrasonography in the diagnosis of pancreatic ductal carcinoma.

Toshiyuki Uekitani, Seiji Kaino, Hirofumi Harima, Shigeyuki Suenaga, Manabu Sen-Yo, Isao Sakaida

Open access · diamondAbstract read
In one paragraph

Article in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Imaging modalities for characterising focal pancreatic lesions.The Cochrane database of systematic reviews · 2017
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Contrast enhanced ultrasound for solid pancreatic lesions: Does timing after contrast injection also matter?Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Toshiyuki UekitaniDepartment of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Japan.
Seiji KainoDepartment of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Japan.
Hirofumi HarimaDepartment of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Japan.
Shigeyuki SuenagaDepartment of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Japan.
Manabu Sen-YoDepartment of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Japan.
Isao SakaidaDepartment of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Japan.
Yamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsDistinguishing pancreatic ductal carcinoma (DC) from other pancreatic masses remains challenging. This study aims at evaluating the efficacy of contrast-enhanced harmonic endoscopic ultrasonography (CEH-EUS) in the diagnosis of DC. PATIENTS AND

methodsForty-nine patients with solid pancreatic mass lesions underwent CEH-EUS. EUS (B-mode) was used to evaluate the inner echoes, distributions, and borders of the masses. The vascular patterns of the masses were evaluated with CEH-EUS at 30-50 s (early phase) and 70-90 s (late phase) after the administration of Sonazoid®.

resultsThe final diagnoses included DCs (37), mass-forming pancreatitis (6), endocrine neoplasms (3), a solid pseudopapillary neoplasm (1), a metastatic carcinoma (1), and an acinar cell carcinoma (1). The sensitivity, specificity, and accuracy of the diagnoses of DC in hypoechoic masses using EUS (B-mode) were 89.2%, 16.7%, and 71.4%, respectively. The sensitivity, specificity, and accuracy for the diagnosis of DC in hypovascular masses using CEH-EUS were 73.0%, 91.7%, and 77.6% in the early phase and 83.8%, 91.7%, and 85.7% in the late phase, respectively.

conclusionsCEH-EUS for the diagnosis of DC is superior to EUS. CEH-EUS in the late phase was particularly efficacious in the diagnosis of DC.

Indexed as

AdultAgedAged, 80 and overCarcinoma, Pancreatic DuctalContrast MediaEndosonographyFemaleHumansMaleMiddle AgedPancreatic NeoplasmsProspective StudiesSensitivity and SpecificityContrast Media

Identifiers

PMID27184637
PMCPMC4898088
OpenAlexW2373399106

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.