ArticleBMC infectious diseases2016
Detecting spatial-temporal cluster of hand foot and mouth disease in Beijing, China, 2009-2014.
Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Epidemiological characteristics and spatiotemporal analysis of hand-foot-mouth disease in Shandong Province, China.International health · 2026Article
- Analysis of the Spatiotemporal Distribution and Evolutionary Trends of Scrub Typhus in Jiangsu Province from 2006 to 2023.Journal of epidemiology and global health · 2025Article
- Analyzing the spatiotemporal effects of meteorological factors on hand, foot and mouth disease using mixed geographically and temporally weighted autoregressive models.Scientific reports · 2025Article
- Spatio-temporal distribution and influencing factors of norovirus outbreaks in Beijing, China from 2016 to 2020.BMC infectious diseases · 2023Article
- Spatiotemporally comparative analysis of three common infectious diseases in China during 2013-2015.BMC infectious diseases · 2022Article
- Spatiotemporal analyses of foot and mouth disease outbreaks in cattle farms in Chiang Mai and Lamphun, Thailand.BMC veterinary research · 2020Article
- Transmission center and driving factors of hand, foot, and mouth disease in China: A combined analysis.PLoS neglected tropical diseases · 2020Article
- Transmission dynamics of brucellosis: Mathematical modelling and applications in China.Computational and structural biotechnology journal · 2020Review
- Epidemiological study on hand, foot and mouth disease in Tongzhou District, Beijing, 2013-2017.The Journal of international medical research · 2019Article
- Predicting the outbreak of hand, foot, and mouth disease in Nanjing, China: a time-series model based on weather variability.International journal of biometeorology · 2018Article
- Using the Kulldorff's scan statistical analysis to detect spatio-temporal clusters of tuberculosis in Qinghai Province, China, 2009-2016.BMC infectious diseases · 2017Article
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11 authors.
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Abstract
backgroundThe incidence of hand, foot, and mouth disease (HFMD) is extremely high, and has constituted a huge disease burden throughout Beijing in recent years. This study aimed to determine the spatiotemporal distribution and epidemic characteristics of HFMD.
methodsDescriptive statistics was used to analyze the data and estimate the epidemic peaks in 2009-2014. Space-time scanning detected spatiotemporal clusters and identified high-risk locations. Global and local Moran's I statistics were used to measure the spatial autocorrelation. Geocoding was performed in ArcGIS, based on the present address codes of the patients and the centroids of the towns. Maps were created in ArcGIS to show the geographic spread of HFMD.
resultsIn total, 220,451probable cases of HFMD were reported in Beijing between January 2009 and December 2014: 12,749 (5.78 %) were laboratory confirmed, and 35 (0.02 %) were fatal. The median age of reported cases was 3.12 years (interquartile range 1.96-4.39). Coxsackievirus A16 (CV-A16), enterovirus 71 (EV-A71), and other enteroviruses accounted for 39.31, 35.36, and 25.33 % of the 12,749 confirmed cases, respectively. Many more severe cases were caused by EV-A71 (χ (2) = 186.41, df = 1, P < 0.001) and other enteroviruses (χ (2) = 156.44, df = 1, P < 0.001) than by CV-A16. A large single distinct peak occurred between May and July each year. Spatiotemporal clusters of HFMD were identified in Beijing during 2009-2014. The most likely clusters were detected and tended to move from the southwest (Fengtai and Daxing) southeastwards to Daxing and Tongzhou in 2009-2014. The incidence of HFMD was not randomly distributed, but showed global and local spatial autocorrelations.
conclusionsThere were obvious spatiotemporal clusters of HFMD in Beijing in 2009-2014. High-incidence areas mainly occurred at the junctions of urban and rural zones. More attention should be paid to the epidemiological and spatiotemporal characteristics of HFMD to establish new strategies for its control. Health issues should be especially promoted in kindergartens and at urban-rural junctions.
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