Evidence map›Paper›PMID 27184068›Full record

Trial reportMolecular imaging and biology2016

A Feasibility Study Showing [

Spencer C Behr, Rahul Aggarwal, Youngho Seo, Carina M Aparici, Emily Chang, Kenneth T Gao, Dora H Tao, Eric J Small, Michael J Evans

Abstract readClinical Trial
In one paragraph

Trial report in Molecular imaging and biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  6. Article
  7. The Evaluation ofMolecular imaging and biology · 2021
    Article
  8. Manipulating the In Vivo Behaviour ofInternational journal of molecular sciences · 2020
    Article
  9. Quantitative and Qualitative Improvement of Low-Count [Molecular imaging and biology · 2020
    Article
  10. Article
  11. Article
  12. Noninvasive Measurement of mTORC1 Signaling withClinical cancer research : an official journal of the American Association for Cancer Research · 2017
    Article
  13. Development of aACS omega · 2017
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Spencer C BehrDepartment of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA.
Rahul AggarwalDepartment of Medicine, University of California, 505 Parnassus Avenue, San Francisco, CA, 94143, USA.
Youngho SeoDepartment of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA.
Carina M ApariciDepartment of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA.
Emily ChangDepartment of Medicine, University of California, 505 Parnassus Avenue, San Francisco, CA, 94143, USA.
Kenneth T GaoDepartment of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA.
Dora H TaoDepartment of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA.
Eric J SmallDepartment of Medicine, University of California, 505 Parnassus Avenue, San Francisco, CA, 94143, USA.
Michael J EvansDepartment of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA. michael.evans@ucsf.edu.
University of California System · USUniversity of California, San Francisco · USBerry (United States) · US

Funding

Translational InformaticsP30CA082103 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jennifer Leigh Clarke · 1999 to 2026
$209.7M
Annotating Oncogene Status in Prostate Cancer with Zr-89-transferrin PETR01CA176671 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI EVANS, MICHAEL JOHN, LEWIS, JASON S. · 2013 to 2017
$3.1M
Pretherapy 124I-MIBG Dosimetry for Planning 131I-MIBG Neuroblastoma TherapyR01CA154561 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEO, YOUNGHO · 2011 to 2016
$1.9M
Noninvasive measurement of oncogenic signaling pathways with 89Zr-transferrinR00CA172695 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EVANS, MICHAEL JOHN · 2014 to 2016
$728k
NCI NIH HHS P30 CA082103NCI NIH HHS R00 CA172695NCI NIH HHS R01 CA154561NCI NIH HHS R01 CA176671
6 · The paper itself

Abstract

purposeThe management of advanced or recurrent prostate cancer is limited in part by the lack of effective imaging agents. Metabolic changes in prostate cancer have previously been exploited for imaging, culminating in the recent US FDA approval of [ PROCEDURES: Eight patients with castrate-resistant prostate cancer were enrolled in this single-center feasibility study. All patients had evidence of metastatic disease by standard of care imaging [X-ray computed tomography (CT), bone scan, or magnetic resonance imaging (MRI)] prior to PET with [

resultsAt 1- and 2-h imaging times post injection, there were no detectable lesions with [

conclusionsOur preliminary results support that PET with [

Indexed as

AgedBone NeoplasmsCitric AcidFeasibility StudiesGallium RadioisotopesHumansMaleMiddle AgedPositron-Emission TomographyProstatic NeoplasmsCitric AcidGallium Radioisotopes[68Ga]citratemTORC1MYCPET/MRPositron emission tomographyProstate cancer

Identifiers

PMID27184068
PMCPMC6430569
OpenAlexW2394887082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.