Evidence map›Paper›PMID 27183842›Full record

ArticlePediatric radiology2016

Small vertebral cross-sectional area and tall intervertebral disc in adolescent idiopathic scoliosis.

Skorn Ponrartana, Carissa L Fisher, Patricia C Aggabao, Thomas A Chavez, Alexander M Broom, Tishya A L Wren, David L Skaggs, Vicente Gilsanz

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. On growth and scoliosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Review
  7. Article
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  12. Vertebral cross-sectional area: an orphan phenotype with potential implications for female spinal health.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Skorn PonrartanaDepartment of Radiology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, MS #81, 4650 Sunset Blvd., Los Angeles, CA, 90027, USA.
Carissa L FisherDepartment of Radiology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, MS #81, 4650 Sunset Blvd., Los Angeles, CA, 90027, USA.
Patricia C AggabaoDepartment of Radiology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, MS #81, 4650 Sunset Blvd., Los Angeles, CA, 90027, USA.
Thomas A ChavezDepartment of Pediatrics, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Alexander M BroomDepartment of Orthopaedic Surgery, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Tishya A L WrenDepartment of Orthopaedic Surgery, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
David L SkaggsDepartment of Orthopaedic Surgery, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Vicente GilsanzDepartment of Radiology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, MS #81, 4650 Sunset Blvd., Los Angeles, CA, 90027, USA. vgilsanz@chla.usc.edu.
University of Southern California · USChildren's Hospital of Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhen compared to boys, girls have smaller vertebral cross-sectional area, which conveys a greater spinal flexibility, and a higher prevalence of adolescent idiopathic scoliosis.

objectiveTo test the hypothesis that small vertebral cross-sectional area and tall intervertebral disc height are structural characteristics of patients with adolescent idiopathic scoliosis. MATERIALS AND

methodsUsing multiplanar imaging techniques, measures of vertebral cross-sectional area, vertebral height and intervertebral disc height in the lumbar spine were obtained in 35 pairs of girls and 11 pairs of boys with and without adolescent idiopathic scoliosis of the thoracic spine matched for age, height and weight.

resultsCompared to adolescents without spinal deformity, girls and boys with adolescent idiopathic scoliosis had, on average, 9.8% (6.68 ± 0.81 vs. 7.40 ± 0.99 cm(2); P = 0.0007) and 13.9% (8.22 ± 0.84 vs. 9.55 ± 1.61 cm(2); P = 0.009) smaller vertebral cross-sectional dimensions, respectively. Additionally, patients with adolescent idiopathic scoliosis had significantly greater values for intervertebral disc heights (9.06 ± 0.85 vs. 7.31 ± 0.62 mm and 9.09 ± 0.87 vs. 7.61 ± 1.00 mm for girls and boys respectively; both P ≤ 0.011). Multiple regression analysis indicated that the presence of scoliosis was negatively associated with vertebral cross-sectional area and positively with intervertebral disc height, independent of sex, age and body mass index.

conclusionWe provide new evidence that girls and boys with adolescent idiopathic scoliosis have significantly smaller vertebral cross-sectional area and taller intervertebral disc heights - two major structural determinants that influence trunk flexibility. With appropriate validation, these findings may have implications for the identification of children at the highest risk for developing scoliosis.

Indexed as

AdolescentFemaleHumansLumbar VertebraeMagnetic Resonance ImagingMaleRetrospective StudiesScoliosisTomography, X-Ray ComputedChildrenComputed tomographyIntervertebral discMagnetic resonance imagingMorphologyScoliosisSpineVertebra

Identifiers

PMID27183842
OpenAlexW2385760618

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.