Evidence map›Paper›PMID 27183441›Full record

ArticleNature methods2016

Flyception: imaging brain activity in freely walking fruit flies.

Dhruv Grover, Takeo Katsuki, Ralph J Greenspan

Abstract read
PubMed Publisher
In one paragraph

Article in Nature methods, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. CRASH2p: Closed-loop Two Photon Imaging in a Freely Moving Animal.bioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Lighting Up CaCells · 2021
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Insights from intoxicated Drosophila.Alcohol (Fayetteville, N.Y.) · 2019
    Review
  19. A resource for theeLife · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dhruv GroverKavli Institute for Brain and Mind, University of California, San Diego, La Jolla, California, USA.
Takeo KatsukiKavli Institute for Brain and Mind, University of California, San Diego, La Jolla, California, USA.
Ralph J GreenspanKavli Institute for Brain and Mind, University of California, San Diego, La Jolla, California, USA.

Funding

U of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0M
NINDS NIH HHS P30 NS047101
6 · The paper itself

Abstract

Genetically encoded calcium sensors have enabled monitoring of neural activity in vivo using optical imaging techniques. Linking neural activity to complex behavior remains challenging, however, as most imaging systems require tethering the animal, which can impact the animal's behavioral repertoire. Here, we report a method for monitoring the brain activity of untethered, freely walking Drosophila melanogaster during sensorially and socially evoked behaviors to facilitate the study of neural mechanisms that underlie naturalistic behaviors.

Indexed as

AnimalsBehavior, AnimalBrainCalciumDrosophila melanogasterFluorescent DyesNervous System Physiological PhenomenaNeuronsOptical ImagingWalkingCalciumFluorescent Dyes

Identifiers

PMID27183441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.