Evidence map›Paper›PMID 27183054›Full record

ArticleInvestigative ophthalmology & visual science2016

Objective Measurement of Fusional Vergence Ranges and Heterophoria in Infants and Preschool Children.

Vidhyapriya Sreenivasan, Erin E Babinsky, Yifei Wu, T Rowan Candy

Open access · goldAbstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. How Do Most Young Moderate Hyperopes Avoid Strabismus?Investigative ophthalmology & visual science · 2023
    Article
  5. Vergence and accommodation responses in the control of intermittent exotropia.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023
    Article
  6. The role of binocular vision in the control and development of visually guided upper limb movements.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. The heterophoria of 3-5 year old children as a function of viewing distance and target type.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2017
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Vidhyapriya Sreenivasan
Erin E Babinsky
Yifei Wu
T Rowan Candy
Indiana University Bloomington · US

Funding

Accommodation and Defocus in the Infant Visual SystemR01EY014460 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI CANDY, T ROWAN · 2003 to 2025
$7.5M
Core Support for Vision Research at Indiana UniversityP30EY019008 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI BURNS, STEPHEN A · 2009 to 2013
$2.1M
NEI NIH HHS P30 EY019008NEI NIH HHS R01 EY014460
6 · The paper itself

Abstract

purposeBinocular alignment typically includes motor fusion compensating for heterophoria. This study evaluated heterophoria and then accommodation and vergence responses during measurement of fusional ranges in infants and preschoolers.

methodsPurkinje image eye tracking and eccentric photorefraction (MCS PowerRefractor) were used to record the eye alignment and accommodation of uncorrected infants (n = 17; 3-5 months old), preschoolers (n = 19; 2.5-5 years), and naïve functionally emmetropic adults (n = 14; 20-32 years; spherical equivalent [SE], +1 to -1 diopters [D]). Heterophoria was derived from the difference between monocular and binocular alignments while participants viewed naturalistic images at 80 cm. The presence or absence of fusion was then assessed after base-in (BI) and base-out (BO) prisms (2-40 prism diopters [pd]) were introduced.

resultsMean (±SD) SE refractions were hyperopic in infants (+2.4 ± 1.2 D) and preschoolers (+1.1 ± 0.6 D). The average exophoria was similar (P = 0.11) across groups (Infants, -0.79 ± 2.5 pd; Preschool, -2.43 ± 2.0 pd; Adults, -1.0 ± 2.7 pd). Mean fusional vergence range also was similar (P = 0.1) for BI (Infants, 11.2 ± 2.5 pd; Preschool, 8.8 ± 2.8 pd; Adults, 11.8 ± 5.2 pd) and BO (Infants, 14 ± 6.6 pd; Preschool, 15.3 ± 8.3 pd; Adults, 20 ± 9.2 pd). Maximum change in accommodation to the highest fusible prism was positive (increased accommodation) for BO (Infants, 1.69 ± 1.4 D; Preschool, 1.35 ± 1.6 D; Adults, 1.22 ± 1.0 D) and negative for BI (Infants, -0.96 ± 1.0 D; Preschool, -0.78 ± 0.6 D; Adults, -0.62 ± 0.3 D), with a similar magnitude across groups (BO, P = 0.6; BI, P = 0.4).

conclusionsDespite typical uncorrected hyperopia, infants and preschoolers exhibited small exophorias at 80 cm, similar to adults. All participants demonstrated substantial fusional ranges, providing evidence that even 3- to 5-month-old infants can respond to a large range of image disparities.

Indexed as

Accommodation, OcularAdolescentAdultChildChild, PreschoolConvergence, OcularDisease ProgressionExotropiaFemaleHumansHyperopiaInfantMaleOculomotor MusclesPrognosisTime Factors

Identifiers

PMID27183054
PMCPMC4874477
OpenAlexW2403746482

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.