ArticleGenetics2016
Development and Genetic Characterization of an Advanced Backcross-Nested Association Mapping (AB-NAM) Population of Wild × Cultivated Barley.
Article in Genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Haplotype-based nested association mapping for net form net blotch response in Australian barley.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Article
- Unlocking salt tolerance from Fertile Crescent wild barley: evolutionary and physiological mechanisms in introgressed lines.Scientific reports · 2026Article
- Enhancing salinity tolerance in barley: harnessing introgressed nested genomes from the wild ancestor Hordeum spontaneum.BMC plant biology · 2025Article
- Crop wild relative populations of Beta vulgaris as source for genome-wide association mapping of complex traits.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Joint linkage and association analysis identifies genomic regions and candidate genes for yield-related traits in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Identification of Quantitative Trait Loci Associated with Plant Adaptation Traits Using Nested Association Mapping Population.Plants (Basel, Switzerland) · 2024Article
- A platform for whole-genome speed introgression from Aegilops tauschii to wheat for breeding future crops.Nature protocols · 2024Review
- Fast integration and accumulation of beneficial breeding alleles through an AB-NAMIC strategy in wheat.Plant communications · 2023Article
- Genomics-driven breeding for local adaptation of durum wheat is enhanced by farmers' traditional knowledge.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Evaluating Introgression Sorghum Germplasm Selected at the Population Level While Exploring Genomic Resources as a Screening Method.Plants (Basel, Switzerland) · 2023Article
- Genome-wide association study as a powerful tool for dissecting competitive traits in legumes.Frontiers in plant science · 2023Review
- Identification of two new QTLs of maize (Zea mays L.) underlying kernel row number using the HNAU-NAM1 population.BMC genomics · 2022Article
- Article
- Genetic dissection of maize plant architecture using a novel nested association mapping population.The plant genome · 2022Article
- Genomic interventions for sustainable agriculture.Plant biotechnology journal · 2020Review
- Multi-parent populations in crops: a toolbox integrating genomics and genetic mapping with breeding.Heredity · 2020Review
- Genetic architecture of agronomic and quality traits in a nested association mapping population of spring wheat.The plant genome · 2020Article
- Exploration of the Yield Potential of Mesoamerican Wild Common Beans From Contrasting Eco-Geographic Regions by Nested Recombinant Inbred Populations.Frontiers in plant science · 2020Article
- Genetic Architecture of Chilling Tolerance in Sorghum Dissected with a Nested Association Mapping Population.G3 (Bethesda, Md.) · 2019Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability to access alleles from unadapted germplasm collections is a long-standing problem for geneticists and breeders. Here we developed, characterized, and demonstrated the utility of a wild barley advanced backcross-nested association mapping (AB-NAM) population. We developed this population by backcrossing 25 wild barley accessions to the six-rowed malting barley cultivar Rasmusson. The 25 wild barley parents were selected from the 318 accession Wild Barley Diversity Collection (WBDC) to maximize allelic diversity. The resulting 796 BC2F4:6 lines were genotyped with 384 SNP markers, and an additional 4022 SNPs and 263,531 sequence variants were imputed onto the population using 9K iSelect SNP genotypes and exome capture sequence of the parents, respectively. On average, 96% of each wild parent was introgressed into the Rasmusson background, and the population exhibited low population structure. While linkage disequilibrium (LD) decay (r(2) = 0.2) was lowest in the WBDC (0.36 cM), the AB-NAM (9.2 cM) exhibited more rapid LD decay than comparable advanced backcross (28.6 cM) and recombinant inbred line (32.3 cM) populations. Three qualitative traits: glossy spike, glossy sheath, and black hull color were mapped with high resolution to loci corresponding to known barley mutants for these traits. Additionally, a total of 10 QTL were identified for grain protein content. The combination of low LD, negligible population structure, and high diversity in an adapted background make the AB-NAM an important tool for high-resolution gene mapping and discovery of novel allelic variation using wild barley germplasm.
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