ArticlePloS one2016
First Description of Hepacivirus and Pegivirus Infection in Domestic Horses in China: A Study in Guangdong Province, Heilongjiang Province and Hong Kong District.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 42 citations in OpenAlex.
- First Detection and Phylogenetic Analysis of Equine Hepacivirus (EqHV) in Iran.Veterinary medicine and science · 2026Article
- Article
- Detection of Equine Parvovirus-Hepatitis Virus and Equine Hepacivirus in Archived Sera from Horses in France and Australia.Viruses · 2024Article
- Article
- European College of Equine Internal Medicine consensus statement on equine flaviviridae infections in Europe.Journal of veterinary internal medicine · 2022Article
- Dose-Dependent Hepacivirus Infection Reveals Linkage between Infectious Dose and Immune Response.Microbiology spectrum · 2022Article
- Equine Hepacivirus: A Systematic Review and a Meta-Analysis of Serological and Biomolecular Prevalence and a Phylogenetic Update.Animals : an open access journal from MDPI · 2022Review
- First identification and genomic characterization of equine hepacivirus sub-type 3 strain in China.Virus genes · 2020Article
- Viral Diseases that Affect Donkeys and Mules.Animals : an open access journal from MDPI · 2020Review
- PCR-based screening and phylogenetic analysis of rat pegivirus (RPgV) carried by rodents in China.The Journal of veterinary medical science · 2020Article
- Equine pegiviruses cause persistent infection of bone marrow and are not associated with hepatitis.PLoS pathogens · 2020Article
- Article
- Emergence of Getah Virus Infection in Horse With Fever in China, 2018.Frontiers in microbiology · 2019Article
- Viral testing of 18 consecutive cases of equine serum hepatitis: A prospective study (2014-2018).Journal of veterinary internal medicine · 2019Article
- Identification and genetic characterization of a novel parvovirus associated with serum hepatitis in horses in China.Emerging microbes & infections · 2018Article
- Roles of the 5' Untranslated Region of Nonprimate Hepacivirus in Translation Initiation and Viral Replication.Journal of virology · 2018Article
- The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China.BioMed research international · 2018Article
- Identification and genetic characterization of hepacivirus and pegivirus in commercial equine serum products in China.PloS one · 2017Article
- Differential Infection Patterns and Recent Evolutionary Origins of Equine Hepaciviruses in Donkeys.Journal of virology · 2017Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since 2012, three viruses, known as equine hepacivirus (EqHV), equine pegivirus (EPgV) and Theiler's disease-associated virus (TDAV), have been discovered in equines. Given that these viruses are the newest members of the Flaviviridae family, genomic information concerning circulating EqHV, EPgV and TDAV strains around the world is limited. To date, no genetic surveillance studies have been performed on these three viruses in the equine population of China. Here, a total of 177 serum samples were collected from equines across China between 2014 and 2015. Using PCR, we detected viral RNA in the serum samples, six of which were EqHV positive and two of which were EPgV positive. Co-infection with the two viruses was not observed among the Chinese equines studied, and TDAV RNA was not detected in the equine serum samples collected for this study. Phylogenetic analysis of partial NS5B open reading frame (ORF), NS3 ORF, and 5' untranslated region nucleotide sequences from EqHV as well as partial NS3 ORF sequence from EPgV indicated that EqHV and EPgV have evolved into two main clades by themselves, both of which are circulating in China. Based on the partial NS5B and NS3 ORF sequences of EqHV, the sequences of one clade were also split into two subclades. This study enriches our knowledge of the geographic distribution of these three equine viruses.
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