Evidence map›Paper›PMID 27182200›Full record

ArticleJournal of substance use

The influence of family and social problems on treatment outcomes of persons with co-occurring substance use disorders and PTSD.

Elizabeth C Saunders, Bethany M McLeman, Mark P McGovern, Haiyi Xie, Chantal Lambert-Harris, Andrea Meier

Open access · greenAbstract read
In one paragraph

Article in Journal of substance use. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Validity of a brief egocentric social network assessment in adults with alcohol use disorder: Direct comparison of 5-alter and 20-alter versions.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elizabeth C SaundersDartmouth Psychiatric Research Center, Geisel School of Medicine at Dartmouth, 85 Mechanic Street, Suite B4-1, Lebanon, NH, USA.
Bethany M McLemanDartmouth Psychiatric Research Center, Geisel School of Medicine at Dartmouth, 85 Mechanic Street, Suite B4-1, Lebanon, NH, USA.
Mark P McGovernDepartment of Psychiatry and of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Haiyi XieDepartment of Community & Family Medicine, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.
Chantal Lambert-HarrisDepartment of Psychiatry, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.
Andrea MeierDepartment of Psychiatry, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.
Dartmouth Psychiatric Research Center · US

Funding

Training in the Science of Co-Occurring DisordersT32DA037202 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2014 to 2026
$4.7M
A Stage II Efficacy Study of CBT for PTSD in Community Addiction TreatmentR01DA027650 · NIDA · DARTMOUTH COLLEGE · PI MCGOVERN, MARK P · 2010 to 2013
$2.3M
NIDA NIH HHS R01 DA027650NIDA NIH HHS T32 DA037202
6 · The paper itself

Abstract

objectiveFamily and social problems may contribute to negative recovery outcomes in patients with co-occurring substance use and psychiatric disorders, yet few studies have empirically examined this relationship. This study investigates the impact of family and social problems on treatment outcomes among patients with co-occurring substance use and posttraumatic stress disorder (PTSD).

methodA secondary analysis was conducted using data collected from a randomized controlled trial of an integrated therapy for patients with co-occurring substance use and PTSD. Substance use, psychiatric symptoms, and social problems were assessed. Longitudinal outcomes were analyzed using generalized estimating equations (GEE) and multiple linear regression.

resultsAt baseline, increased family and social problems were associated with more severe substance use and psychiatric symptoms. Over time, all participants had comparable decreases in substance use and psychiatric problem severity. However, changes in family and social problem severity were predictive of PTSD symptom severity, alcohol use, and psychiatric severity at follow-up.

conclusionsFor patients with co-occurring substance use and PTSD, family and social problem severity is associated with substance use and psychiatric problem severity at baseline and over time. Targeted treatment for social and family problems may be optimal.

Indexed as

family and social problemsposttraumatic stress disordersubstance use

Identifiers

PMID27182200
PMCPMC4864012
OpenAlexW2037622927

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.